Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7159138 | 0.78 | MAPT (0.45) | GAAMAPTNOS2HTTKDM4E | |
| SCHEMBL1726909 | 0.72 | GAA (0.46) | GAAMAPTNOS2KDM4EHPGD | |
| SCHEMBL29789697 | 0.71 | MAPT (0.50) | GAAMAPTNOS2KDM4EHPGD | |
| SCHEMBL2255782 | 0.71 | MAPT (0.50) | GAAMAPTNOS2KDM4EHPGD | |
| SCHEMBL11026821 | 0.69 | GAA (0.43) | GAAMAPTKDM4EHPGD | |
| SCHEMBL6607968 | 0.68 | GAA (0.46) | GAAMAPTNOS2KDM4EHPGD | |
| SCHEMBL21145451 | 0.68 | GAA (0.46) | GAAMAPTNOS2KDM4EHPGD | |
| SCHEMBL1285713 | 0.68 | MAPT (0.46) | GAAMAPTNOS2HTTKDM4E | |
| SCHEMBL4389562 | 0.68 | GAA (0.42) | GAAMAPT | |
| SCHEMBL7597347 | 0.67 | GAA (0.37) | GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879563-A4 | NOVEL CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2008-07-16 | — | — | EP | disclosed |
| EP-1879563-A2 | NOVEL CHEMICAL COMPOUNDS | Smithkline Beecham Corporation (US) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006132739-A2 | NOVEL CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-12-14 | — | — | WO | disclosed |