Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | ERN1 | O75460 | 2/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19419899 | 0.93 | CYP2C9 (0.59) | GABRA1GABRB2CYP2C9HIF1ACYP2C19 | |
| SCHEMBL13888086 | 0.88 | HSD17B10 (0.56) | CYP2C9HIF1ACYP2C19HSD17B10ALDH1A1 | |
| SCHEMBL14613260 | 0.88 | HIF1A (0.44) | GABRA1GABRB2CYP2C9HIF1ACYP2C19 | |
| SCHEMBL13888157 | 0.86 | CYP2C9 (0.43) | GABRA1GABRB2CYP2C9HIF1ACYP2C19 | |
| SCHEMBL19419892 | 0.85 | CYP2C9 (0.52) | GABRA1GABRB2CYP2C9HIF1ACYP2C19 | |
| SCHEMBL814134 | 0.84 | TTR (0.41) | GABRA1GABRB2CYP2C9HIF1ACYP2C19 | |
| SCHEMBL13888155 | 0.84 | ERN1 (0.50) | GABRA1GABRB2CYP2C9HIF1ACYP2C19 | |
| SCHEMBL17744510 | 0.84 | ALDH1A1 (0.40) | GABRA1GABRB2CYP2C9HIF1ACYP2C19 | |
| SCHEMBL13888755 | 0.84 | ALDH1A1 (0.40) | GABRA1GABRB2CYP2C9HIF1ACYP2C19 | |
| SCHEMBL21547602 | 0.84 | CYP2C9 (0.38) | GABRA1GABRB2CYP2C9HIF1ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101497692-B | Use of magnetic supported catalyst in polyphenylene oxide preparation | UNIV ZHEJIANG | 2011-03-16 | — | — | CN | claimed |
| CN-101942087-A | Metal ion-hyperbranched polyamide amine complex catalyst and application to preparing polyphenylene oxide (PPO) in water medium | UNIV ZHEJIANG | 2011-01-12 | — | — | CN | claimed |
| CN-101544755-B | Metallic ion-polyvinyl imidazol complex catalyst and preparation method and application thereof | UNIV ZHEJIANG | 2010-12-08 | — | — | CN | claimed |
| CN-101544755-A | Metallic ion-polyvinyl imidazol complex catalyst and preparation method and application thereof | UNIV ZHEJIANG | 2009-09-30 | — | — | CN | claimed |
| CN-101497692-A | Magnetic supported catalyst and use thereof in polyphenylene oxide preparation | UNIV ZHEJIANG (CN) | 2009-08-05 | — | — | CN | claimed |
| CN-101497693-A | Metallic ion-polyamide polyamide-amine complex compound catalyst and use for preparing polyphenylene oxide in aqueous medium | UNIV ZHEJIANG (CN) | 2009-08-05 | — | — | CN | claimed |
| US-8268381-B2 | Methods and systems for coating a medical device | ALLACCEM, INC. (US) | 2012-09-18 | — | — | US | disclosed |
| US-8222239-B2 | quaternary ammonium compounds, conjugated to polymers, used as microbiocides | ALLACCEM, INC. (US) | 2012-07-17 | — | — | US | disclosed |
| US-8188068-B2 | Bridged polycyclic compound based compositions for coating oral surfaces in pets | ALLACCEM, INC. (US) | 2012-05-29 | — | — | US | disclosed |
| US-8153617-B2 | Bridged polycyclic compound based compositions for coating oral surfaces in humans | ALLACCEM, INC. (US) | 2012-04-10 | — | — | US | disclosed |
| US-8067403-B2 | Methods and systems for preparing an antimicrobial composition | ALLACCEM, INC. (US) | 2011-11-29 | — | — | US | disclosed |
| CN-102060990-A | Magnetic supported catalyst and application thereof in preparing polyphenyleneoxide in aqueous medium | UNIV ZHEJIANG | 2011-05-18 | — | — | CN | disclosed |
| CN-101497692-B | Use of magnetic supported catalyst in polyphenylene oxide preparation | UNIV ZHEJIANG | 2011-03-16 | — | — | CN | disclosed |
| US-20070191409-A1 | Compounds for inhibiting beta-amyloid production and methods of identifying the compounds | ROSKAMP RESEARCH LLC | 2007-08-16 | — | — | US | disclosed |
| US-20070185130-A1 | Compounds for inhibiting beta-amyloid production and methods of identifying the compounds | ROSKAMP RESEARCH LLC | 2007-08-09 | — | — | US | disclosed |
| CN-1328315-C | Method for preparing polyphenyl ether/styrene alloy | UNIV ZHEJIANG (CN) | 2007-07-25 | — | — | CN | disclosed |
| CN-1314758-C | Polymrization method of preparing polyphonyl ether/phenylethylene kind polymer alloy in reactor | UNIV ZHEJIANG (CN) | 2007-05-09 | — | — | CN | disclosed |
| US-20070037855-A1 | Compounds for inhibiting beta-amyloid production and methods of identifying the compounds | ALZHEIMER'S INSTITUTE OF AMERICA, INC. | 2007-02-15 | — | — | US | disclosed |
| CN-1737048-A | Method for preparing polyphenyl ether/styrene alloy | UNIV ZHEJIANG (CN) | 2006-02-22 | — | — | CN | disclosed |
| CN-1718634-A | Polymrization method of preparing polyphonyl ether/phenylethylene kind polymer alloy in reactor | UNIV ZHEJIANG (CN) | 2006-01-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191409-A1 | Compounds for inhibiting beta-amyloid production and methods of identifying the compounds | APP, PSEN1, PSEN2 | GABRA1 1294/4885GABRB2 435/4885CYP2C9 4440/4885 |
| US-20070185130-A1 | Compounds for inhibiting beta-amyloid production and methods of identifying the compounds | APP, PSEN1, PSEN2 | GABRA1 1294/4885GABRB2 435/4885CYP2C9 4440/4885 |
| US-20070037855-A1 | Compounds for inhibiting beta-amyloid production and methods of identifying the compounds | APP, PSEN1, PSEN2 | GABRA1 1294/4885GABRB2 435/4885CYP2C9 4440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.