Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28216941 | 0.84 | PARP10 (0.57) | CA1CA2PARP15PARP10KMT2A | |
| SCHEMBL28131356 | 0.83 | ELANE (0.70) | PARP10ELANEKMT2ASRD5A2HTT | |
| SCHEMBL10593101 | 0.82 | KMT2A (0.57) | HSD17B10ELANEKMT2AESR1RECQL | |
| SCHEMBL43401 | 0.81 | CYP19A1 (0.52) | HSD17B10ELANEKMT2AHTT | |
| SCHEMBL4801933 | 0.81 | F2 (0.53) | — | |
| SCHEMBL15501169 | 0.81 | HSD17B10 (0.58) | HSD17B10CA1CA2PKMTP53 | |
| SCHEMBL6691150 | 0.80 | HSD17B10 (0.52) | HSD17B10CA1CA2PARP15PARP10 | |
| SCHEMBL6697455 | 0.80 | HSD17B10 (0.52) | HSD17B10CA1CA2PARP15PARP10 | |
| SCHEMBL6699565 | 0.80 | HSD17B10 (0.52) | HSD17B10CA1CA2PARP15PARP10 | |
| SCHEMBL6866158 | 0.80 | KMT2A (0.55) | HSD17B10CA1CA2PARP15PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3302493-B1 | INHIBITORS OF CYSTINE-GLUTAMATE TRANSPORTER FOR USE IN TREATING OR PREVENTING SUBSTANCE-RELATED AND ADDICTIVE DISORDERS | UNIV CHINA MEDICAL (TW) | 2021-07-07 | — | — | EP | claimed |
| CN-101346471-B | Triprenyl phenol compound, process for producing triisoprenyl phenol compound, and thrombolysis promoter | TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY TLO CO.,LTD. (JP) | 2016-01-06 | — | — | CN | disclosed |
| WO-2015196086-A1 | NOVEL INHIBITORS OF SYSTEM Xc(-) | The University of Montana, Missoula, MT (US) | 2015-12-23 | — | — | WO | disclosed |
| CN-102321092-B | Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer | UNIV TOKYO AGRICULTURE & TECHNOLOGY TLO CO LTD (JP) | 2015-01-14 | — | — | CN | disclosed |
| CN-102304131-B | Triprenyl phenol compound and its preparing method, and thrombolysis enhancer | NOKODAI TLO KK | 2014-07-16 | — | — | CN | disclosed |
| CN-102304131-A | Triprenyl phenol compound and thrombolysis enhancer | NOKODAI TLO KK | 2012-01-04 | — | — | CN | disclosed |
| US-7589170-B1 | Synthesis of cyclic peptides | THE UNIVERSITY OF QUEENSLAND (AU) | 2009-09-15 | — | — | US | disclosed |
| US-7589170-B1 | Synthesis of cyclic peptides | THE UNIVERSITY OF QUEENSLAND (AU) | 2009-09-15 | — | — | US | disclosed |
| CN-101346471-A | Triprenyl phenol compound, process for producing triisoprenyl phenol compound, and thrombolysis promoter | UNIV TOKYO AGRICULTURE & TECHNOLOGY TLO CO LTD (JP) | 2009-01-14 | — | — | CN | disclosed |
| EP-1404864-A4 | REGULATION OF NEURONAL FUNCTION THROUGH METABOTROPIC GLUTAMATE RECEPTOR SIGNALING PATHWAYS | UNIV ROCKEFELLER (US) | 2008-05-28 | — | — | EP | disclosed |
| EP-0843660-A1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1998-05-27 | — | — | EP | disclosed |
| EP-0842176-A1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1998-05-20 | — | — | EP | disclosed |
| US-5696148-A | POTENT ANTAGONIST OF METABOTROPIC GLUTAMATE RECEPTORS; TREATING EPILEPSY, PARKINSON'S DISEASE, HUNTINGTON'S DISEASE, BRAIN DISORDER AND ALZHEIMER'S DISEASE | NOVO NORDISK A/S (DK) | 1997-12-09 | — | — | US | disclosed |
| WO-1997005109-A1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1997-02-13 | — | — | WO | disclosed |
| WO-1997005137-A1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1997-02-13 | — | — | WO | disclosed |
| EP-0750621-A1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1997-01-02 | — | — | EP | disclosed |
| US-5536721-A | Thieno[2,3-b-indole derivatives and their use for treating central nervous system diseases related to the metabotropic glutamate receptor system | NOVO NORDISK A/S (DK) | 1996-07-16 | — | — | US | disclosed |
| WO-1996015099-A1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1996-05-23 | — | — | WO | disclosed |
| WO-1996015100-A1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1996-05-23 | — | — | WO | disclosed |
| WO-1995025110-A1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1995-09-21 | — | — | WO | disclosed |