SCHEMBL43401

SCHEMBL43401

NCC(=O)Oc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.52
PRSS1 P07477 1/20 0.49
PRSS2 P07478 1/20 0.49
PRSS3 P35030 1/20 0.49
ELANE P08246 1/20 0.47
TDP1 Q9NUW8 2/20 0.45
ATM Q13315 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
ALOX15 P16050 2/20 0.45
AOC2 O75106 2/20 0.44
MAOA P21397 2/20 0.44
MAOB P27338 2/20 0.44
DAO P14920 1/20 0.44
HSD17B10 Q99714 2/20 0.44
HPGD P15428 1/20 0.44
MAPT P10636 4/20 0.44
ALDH1A1 P00352 2/20 0.44
ADRA2C P18825 1/20 0.43
KMT2A Q03164 2/20 0.42
LMNA P02545 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL10492602 0.98 CYP19A1 (0.50) CYP19A1PRSS1PRSS2PRSS3ELANE
SCHEMBL27980699 0.98 CYP19A1 (0.50) CYP19A1PRSS1PRSS2PRSS3ELANE
Water SCHEMBL27902318 0.98 CYP19A1 (0.50) CYP19A1PRSS1PRSS2PRSS3ELANE
SCHEMBL28226305 0.98 CYP19A1 (0.50) CYP19A1PRSS1PRSS2PRSS3ELANE
Ammonia Solution, Strong SCHEMBL28260172 0.98 CYP19A1 (0.50) CYP19A1PRSS1PRSS2PRSS3ELANE
SCHEMBL28108373 0.98 CYP19A1 (0.50) CYP19A1PRSS1PRSS2PRSS3ELANE
Hydrochloric Acid SCHEMBL7318909 0.98 CYP19A1 (0.50) CYP19A1PRSS1PRSS2PRSS3ELANE
SCHEMBL29070669 0.92 PARP10 (0.53) CYP19A1ELANEMAOAADRA2C
Sulfuric Acid SCHEMBL11051925 0.92 CYP19A1 (0.46) CYP19A1PRSS1PRSS2PRSS3ELANE
SCHEMBL10456820 0.90 CYP19A1 (0.45) CYP19A1PRSS1PRSS2PRSS3ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1841 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240116998-A1 GLUCAGON-LIKE PEPTIDE-1 RECEPTOR ANTAGONISTS INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION 2024-04-11 US claimed
US-20240058422-A1 GLUCAGON-LIKE PEPTIDE-1 RECEPTOR ANTAGONISTS INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION 2024-02-22 US claimed
WO-2024030934-A2 GLUCAGON-LIKE PEPTIDE-1 RECEPTOR ANTAGONISTS INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2024-02-08 WO claimed
EP-4294826-A1 GLUCAGON-LIKE PEPTIDE-1 RECEPTOR ANTAGONISTS Indiana University Research and Technology Corporation (US) 2023-12-27 EP claimed
US-20230046947-A1 REACTIVE CONJUGATES DEBIOPHARM RESEARCH & MANUFACTURING S.A. (CH) 2023-02-16 US claimed
EP-3703611-B1 PHOTO-RESPONSIVE SHAPE CHANGING POLYMER COMPOSITION FOR COLORED OPTICAL LENS NAYAM INNOVATIONS PVT LTD (IN) 2022-11-23 EP claimed
EP-4069311-A1 REACTIVE CONJUGATES Debiopharm Research & Manufacturing SA (CH) 2022-10-12 EP claimed
WO-2022177878-A1 GLUCAGON-LIKE PEPTIDE-1 RECEPTOR ANTAGONISTS INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2022-08-25 WO claimed
US-11339281-B2 Photo-responsive shape changing polymer composition for colored optical lens NAYAM INNOVATIONS PVT LTD (IN) 2022-05-24 US claimed
WO-2021110860-A1 REACTIVE CONJUGATES DEBIOPHARM RESEARCH & MANUFACTURING S.A. (CH) 2021-06-10 WO claimed
EP-0066103-B1 PROCESS FOR THE REDUCTION OF REDUCIBLE GROUPS, AND ITS APPLICATION Eckert, Heiner, dr. (DE) 1985-08-28 EP claimed
US-4537713-A Process for the reduction of reducible groups and its use ECKERT HEINER (DE) 1985-08-27 US claimed
EP-0030871-B1 METHOD OF OPTICAL RESOLUTION OF (+/-)-PHENYL GLYCIN AND/OR (+/-)-CAMPHOR SULFONIC ACID Nohira, Hiroyuki (JP) 1984-05-09 EP claimed
EP-0096319-A1 Method for preventing scale deposition in the polymerization of ethylenically unsaturated monomers Shin-Etsu Chemical Co., Ltd. (JP) 1983-12-21 EP claimed
EP-0091965-A1 PROCESS FOR PREVENTING DEPOSITION OF POLYMER SCALE DURING POLYMERIZATION OF VINYL MONOMER SHIN-ETSU CHEMICAL CO., LTD. (JP) 1983-10-26 EP claimed
EP-0030871-A1 Method of optical resolution of (+/-)-phenyl glycin and/or (+/-)-camphor sulfonic acid Nohira, Hiroyuki (JP) 1981-06-24 EP claimed
US-4113959-A METHOD FOR RESOLVING AMINO AND AMMONIUM COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1978-09-12 US claimed
US-4111980-A Process for preparing optically active phenyl glycine STAMICARBON, B.V. (NL) 1978-09-05 US claimed
US-4093653-A RESOLUTION STAMICARBON, B.V. (NL) 1978-06-06 US claimed
US-4061628-A Intermediates for producing semi-synthetic penicillins and cephalosporins and methods of production AMERICAN HOME PRODUCTS CORPORATION (US) 1977-12-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240058422-A1 GLUCAGON-LIKE PEPTIDE-1 RECEPTOR ANTAGONISTS GLP1R, GCGR, GPR119 CYP19A1 1368/4885PRSS1 996/4885PRSS2 1188/4885
US-20240116998-A1 GLUCAGON-LIKE PEPTIDE-1 RECEPTOR ANTAGONISTS GLP1R, GCGR, GPR119 CYP19A1 1368/4885PRSS1 996/4885PRSS2 1188/4885
US-20230046947-A1 REACTIVE CONJUGATES FCGR3B, FCGR1A, FCGR2A CYP19A1 3623/4885PRSS1 4208/4885PRSS2 4155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.