Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20146 | 0.89 | MIF (0.40) | LMNAMIFCYP2D6SRC | |
| SCHEMBL165792 | 0.89 | MIF (0.40) | LMNAMIFCYP2D6SRC | |
| SCHEMBL27749125 | 0.87 | MIF (0.39) | RAB9ALMNAMIFCYP2D6SRC | |
| SCHEMBL2550722 | 0.83 | MIF (0.36) | LMNAMIFCYP2D6SRC | |
| SCHEMBL28588784 | 0.83 | MIF (0.36) | LMNAMIFCYP2D6SRC | |
| SCHEMBL28953538 | 0.83 | MIF (0.36) | LMNAMIFCYP2D6SRC | |
| Silicate SCHEMBL11175801 | 0.80 | SRC (0.35) | LMNAMEN1KMT2AMIFL3MBTL1 | |
| Urea SCHEMBL17063544 | 0.80 | CYP2C19 (0.41) | LMNANPSR1SMN1; SMN2CYP2D6SRC | |
| SCHEMBL2024304 | 0.78 | — | — | |
| SCHEMBL6321421 | 0.78 | ACP3 (0.42) | ALDH1A1HSD17B10APAF1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1914255-B1 | ALIPHATIC POLYISOCYANATE PREPOLYMERS AND POLYURETHANE RESIN COATING COMPOSITIONS USING THE SAME | COVESTRO DEUTSCHLAND AG (DE) | 2020-04-15 | — | — | EP | disclosed |
| US-8378053-B2 | From an aliphatic isocyanurate group-containing polyisocyanate and a short-chain diol | BAYER MATERIALSCIENCE AG (DE) | 2013-02-19 | — | — | US | disclosed |
| US-20080114144-A1 | Aliphatic polyisocyanate prepolymers and polyurethane resin coating compositions using the same | COVESTRO DEUTSCHLAND AG (DE) | 2008-05-15 | — | — | US | disclosed |
| EP-1914255-A2 | Aliphatic polyisocyanate prepolymers and polyurethane resin coating compositions using the same | Bayer MaterialScience AG (DE) | 2008-04-23 | — | — | EP | disclosed |