SCHEMBL2550722

SCHEMBL2550722

N=C=O.O=C=NC(N=C=O)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MIF P14174 3/20 0.36
CYP2D6 P10635 1/20 0.33
SRC P12931 1/20 0.33
LMNA P02545 2/20 0.32
MAPK1 P28482 1/20 0.32
DPP4 P27487 2/20 0.32
TSHR P16473 2/20 0.32
F2 P00734 1/20 0.32
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
TRPA1 O75762 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28953538 1.00 MIF (0.36) MIFCYP2D6SRCLMNAMAPK1
SCHEMBL165792 0.93 MIF (0.40) MIFCYP2D6SRCLMNAMAPK1
SCHEMBL20146 0.93 MIF (0.40) MIFCYP2D6SRCLMNAMAPK1
SCHEMBL27749125 0.91 MIF (0.39) MIFCYP2D6SRCLMNAMAPK1
Toluene SCHEMBL1149402 0.91 LMNA (0.39) MIFCYP2D6LMNAMAPK1TSHR
SCHEMBL28588784 0.87 MIF (0.36) MIFCYP2D6SRCLMNAMAPK1
SCHEMBL4587655 0.83 ALDH1A1 (0.39) MIFCYP2D6SRCLMNA
Urea SCHEMBL17063544 0.83 CYP2C19 (0.41) CYP2D6SRCLMNAMAPK1CES2
Silicate SCHEMBL11175801 0.83 SRC (0.35) MIFCYP2D6SRCLMNAMAPK1
SCHEMBL28839465 0.83 MIF (0.36) MIFCYP2D6SRCLMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2561246-B1 DAMPER BEARING WITH TAPERING END FACES AND METHOD FOR PRODUCTION THEREOF BASF SE (DE) 2020-02-26 EP disclosed
US-9767961-B2 Composite electronic component NGK INSULATORS, LTD. (JP) 2017-09-19 US disclosed
US-8789820-B2 Damper bearing with tapering end faces and method for the production thereof BASF SE (DE) 2014-07-29 US disclosed
EP-2561246-A1 DAMPER BEARING WITH TAPERING END FACES AND METHOD FOR PRODUCTION THEREOF BASF SE (DE) 2013-02-27 EP disclosed
US-20120236459-A1 COMPOSITE ELECTRONIC COMPONENT NGK INSULATORS, LTD. (JP) 2012-09-20 US disclosed
EP-2500920-A1 Composite electronic component NGK Insulators, Ltd. (JP) 2012-09-19 EP disclosed
US-20110260382-A1 DAMPER BEARING WITH TAPERING END FACES AND METHOD FOR THE PRODUCTION THEREOF BASF SE (DE) 2011-10-27 US disclosed
WO-2011130909-A1 DAMPER BEARING WITH TAPERING END FACES AND METHOD FOR PRODUCTION THEREOF BASF SE (DE) 2011-10-27 WO disclosed