Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 10/20 | 0.47 |
| ▸ | AR | P10275 | 3/20 | 0.47 |
| ▸ | PGR | P06401 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3653263 | 0.84 | CYP19A1 (0.57) | CYP19A1ARPGRAKR1C3TSHR | |
| SCHEMBL13804526 | 0.84 | CYP19A1 (0.57) | CYP19A1ARPGRAKR1C3TSHR | |
| SCHEMBL6376819 | 0.83 | CYP19A1 (0.52) | CYP19A1ARPGRNR3C2 | |
| SCHEMBL4586771 | 0.82 | AR (0.50) | CYP19A1ARPGRNR3C2 | |
| SCHEMBL14342102 | 0.82 | AR (0.50) | CYP19A1ARPGRNR3C2 | |
| SCHEMBL6849417 | 0.82 | CYP19A1 (0.41) | CYP19A1ARPGRAKR1C3TSHR | |
| SCHEMBL6849024 | 0.81 | CYP19A1 (0.40) | CYP19A1ARPGRAKR1C3TSHR | |
| SCHEMBL13804516 | 0.80 | CYP19A1 (0.49) | CYP19A1ARPGRNR3C2 | |
| SCHEMBL4588011 | 0.80 | CYP19A1 (0.49) | CYP19A1ARPGRNR3C2 | |
| SCHEMBL4588578 | 0.80 | CYP19A1 (0.49) | CYP19A1ARPGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7361645-B2 | Androgenic 7-substituted 11-halogen steroids | BAYER SCHERING PHARMA AG (DE) | 2008-04-22 | — | — | US | disclosed |
| EP-1353938-B1 | ANDROGENIC 7-SUBSTITUTED 11-HALOGENATED STEROIDS | BAYER SCHERING PHARMA AG (DE) | 2008-02-13 | — | — | EP | disclosed |
| US-20050075322-A1 | Androgenic 7-substituted 11-halogen steroids | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2005-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075322-A1 | Androgenic 7-substituted 11-halogen steroids | NR5A1, HSD17B11, HSD11B1 | CYP19A1 14/4885AR 16/4885PGR 174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.