Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.77 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.77 |
| ▸ | F2 | P00734 | 1/20 | 0.77 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Rivaroxaban SCHEMBL3914 | 0.87 | F10 (1.00) | F10ABCB11F2ST14CYP3A4 | |
| Rivaroxaban SCHEMBL7721848 | 0.87 | F10 (1.00) | F10ABCB11F2ST14CYP3A4 | |
| Rivaroxaban SCHEMBL77766 | 0.87 | F10 (1.00) | F10ABCB11F2ST14CYP3A4 | |
| Rivaroxaban SCHEMBL14796329 | 0.86 | F10 (0.98) | F10ABCB11F2ST14CYP3A4 | |
| SCHEMBL21305662 | 0.85 | F10 (0.80) | F10ABCB11F2ST14CYP3A4 | |
| SCHEMBL3375861 | 0.85 | F10 (0.86) | F10ABCB11F2ST14CYP3A4 | |
| SCHEMBL5478295 | 0.85 | F10 (0.85) | F10ABCB11F2ST14CYP3A4 | |
| SCHEMBL13068882 | 0.85 | F10 (0.85) | F10ABCB11F2ST14CYP3A4 | |
| SCHEMBL18427368 | 0.84 | F10 (0.75) | F10ABCB11F2ST14CYP3A4 | |
| SCHEMBL13977416 | 0.83 | F10 (0.74) | F10ABCB11F2ST14CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1689370-B2 | METHOD FOR THE PRODUCTION OF A SOLID, ORALLY APPLICABLE PHARMACEUTICAL COMPOSITION COMPRISING 5-Chlor-N ( { (5-2-oxo-3- [4- (3-oxo-4-morpholinyl)-phenyl]-1, 3- oxazolidin-5-yl}-methyl)-2-thiophencarboxamide | BAYER IP GMBH (DE) | 2016-09-14 | — | — | EP | disclosed |
| EP-1689370-B1 | METHOD FOR THE PRODUCTION OF A SOLID, ORALLY APPLICABLE PHARMACEUTICAL COMPOSITION COMPRISING 5-Chlor-N ( { (5-2-oxo-3- [4- (3-oxo-4-morpholinyl)-phenyl]-1, 3- oxazolidin-5-yl}-methyl)-2-thiophencarboxamide | BAYER HEALTHCARE AG (DE) | 2008-02-13 | — | — | EP | disclosed |