Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 15/20 | 0.45 |
| ▸ | PGR | P06401 | 5/20 | 0.43 |
| ▸ | AR | P10275 | 5/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13804516 | 0.85 | CYP19A1 (0.49) | CYP19A1PGRARNR3C2 | |
| SCHEMBL1897274 | 0.85 | CYP19A1 (0.49) | CYP19A1PGRARNR3C2 | |
| SCHEMBL4588011 | 0.85 | CYP19A1 (0.49) | CYP19A1PGRARNR3C2 | |
| SCHEMBL3999426 | 0.85 | CYP19A1 (0.40) | CYP19A1AR | |
| SCHEMBL6849201 | 0.85 | CYP19A1 (0.40) | CYP19A1AR | |
| SCHEMBL6854222 | 0.85 | CYP19A1 (0.40) | CYP19A1AR | |
| SCHEMBL13809850 | 0.85 | CYP19A1 (0.40) | CYP19A1AR | |
| SCHEMBL13804521 | 0.85 | CYP19A1 (0.40) | CYP19A1AR | |
| SCHEMBL6853911 | 0.85 | CYP19A1 (0.40) | CYP19A1AR | |
| SCHEMBL6852290 | 0.85 | CYP19A1 (0.40) | CYP19A1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7361645-B2 | Androgenic 7-substituted 11-halogen steroids | BAYER SCHERING PHARMA AG (DE) | 2008-04-22 | — | — | US | disclosed |
| EP-1353938-B1 | ANDROGENIC 7-SUBSTITUTED 11-HALOGENATED STEROIDS | BAYER SCHERING PHARMA AG (DE) | 2008-02-13 | — | — | EP | disclosed |
| US-20050075322-A1 | Androgenic 7-substituted 11-halogen steroids | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2005-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075322-A1 | Androgenic 7-substituted 11-halogen steroids | NR5A1, HSD17B11, HSD11B1 | CYP19A1 14/4885PGR 174/4885AR 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.