⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15216237 | 0.92 | — | — | |
| SCHEMBL16847555 | 0.83 | — | — | |
| SCHEMBL1309431 | 0.83 | TDP1 (0.42) | — | |
| SCHEMBL1837224 | 0.83 | KDM4E (0.48) | — | |
| SCHEMBL4682290 | 0.81 | — | — | |
| SCHEMBL1837168 | 0.80 | KDM4E (0.52) | — | |
| SCHEMBL11173620 | 0.80 | KDM4E (0.52) | — | |
| SCHEMBL1839119 | 0.80 | KDM4E (0.52) | — | |
| SCHEMBL28622543 | 0.80 | KDM4E (0.52) | — | |
| SCHEMBL1309360 | 0.80 | KDM4E (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024081668-A2 | LIPID-POLYMER COMPOUNDS, COMPOSITIONS, AND USES THEREOF | MIRUS BIO LLC (US) | 2024-04-18 | — | — | WO | disclosed |
| WO-2023156629-A1 | STEALTH-STABILIZED LIPO-POLYAMINO ACIDS | POLYPEPTIDE THERAPEUTIC SOLUTIONS, S.L. (ES) | 2023-08-24 | — | — | WO | disclosed |
| WO-2023111290-A1 | POLYSARCOSINE-VITAMIN E DERIVATIVES | POLYPEPTIDE THERAPEUTIC SOLUTIONS, S.L. (ES) | 2023-06-22 | — | — | WO | disclosed |
| US-11364189-B2 | Method for the treatment of keratin materials using amide C-glycoside derivatives, and cosmetic composition containing same | L'OREAL (FR) | 2022-06-21 | — | — | US | disclosed |
| US-20210000727-A1 | DITHIAZOCANE COMPOUNDS FOR THE COSMETIC USE THEREOF | L'OREAL (FR) | 2021-01-07 | — | — | US | disclosed |
| US-20190274940-A1 | METHOD FOR THE TREATMENT OF KERATIN MATERIALS USING AMIDE C-GLYCOSIDE DERIVATIVES, AND COSMETIC COMPOSITION CONTAINING SAME | L'OREAL (FR) | 2019-09-12 | — | — | US | disclosed |
| US-20190263770-A1 | METHOD FOR THE TREATMENT OF KERATIN MATERIALS USING ACID, ESTER OR AMIDE C-GLYCOSIDE DERIVATIVES, AND COSMETIC COMPOSITION CONTAINING SAME | L'OREAL (FR) | 2019-08-29 | — | — | US | disclosed |
| EP-3165532-A2 | AURISTATIN DERIVATIVES, LINKER-DRUGS AND LIGAND-DRUG CONJUGATES | Industrial Technology Research Institute (TW) | 2017-05-10 | — | — | EP | disclosed |
| WO-2016149464-A1 | AMINO ACID ACYLATION REAGENTS AND METHODS OF USING THE SAME | REGENERON PHARMACEUTICALS, INC. (US) | 2016-09-22 | — | — | WO | disclosed |
| EP-2966063-A1 | FUNGICIDAL PYRAZOLES | E. I. du Pont de Nemours and Company (US) | 2016-01-13 | — | — | EP | disclosed |
| US-6573266-B1 | Compounds used for treating multitiple sclerosis and encephalomyelitis | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-06-03 | — | — | US | disclosed |
| US-6555537-B2 | Inhibit activity of chemokines, macrophage inflammatory protein-1 (MIP-1 alpha) and RANTES; 1-((4-chlorophenoxy)methyl)-carbonyl-2-methyl-4-(4-fluorobenzyl)piperazine for example | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-04-29 | — | — | US | disclosed |
| US-6541476-B1 | Treating multiple sclerosis or encephalomyelitis in a human | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-04-01 | — | — | US | disclosed |
| US-6534509-B1 | Derivatives are useful as anti-inflammatory agents. This invention is also directed to pharmacetutical compostions for inflammation | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-03-18 | — | — | US | disclosed |
| EP-0988292-B1 | PIPERAZINE DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | SCHERING AG (DE) | 2003-02-12 | — | — | EP | disclosed |
| US-20020177598-A1 | Piperazine derivatives and their use as anti-inflammatory agents | SCHERING AKTIENGSCHELLSCHAFT | 2002-11-28 | — | — | US | disclosed |
| EP-1254899-A2 | Piperazine derivatives and their use as anti-inflammatory agents | Schering Aktiengesellschaft (DE) | 2002-11-06 | — | — | EP | disclosed |
| US-6207665-B1 | TO TREAT INFLAMMATORY DISORDERS IN HUMANS | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-03-27 | — | — | US | disclosed |
| EP-0988292-A2 | PIPERAZINE DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-03-29 | — | — | EP | disclosed |
| WO-1998056771-A2 | PIPERAZINE DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-12-17 | — | — | WO | disclosed |