SCHEMBL1309360

SCHEMBL1309360

NC(=O)NCCCCCCNC(N)=O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.52
MAPK1 P28482 1/20 0.52
HIF1A Q16665 1/20 0.52
ALDH1A1 P00352 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
PAOX Q6QHF9 2/20 0.48
EPHX1 P07099 5/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
ALDH1A2 O94788 1/20 0.46
ALDH2 P05091 1/20 0.46
ALDH1A3 P47895 1/20 0.46
PRMT1 Q99873 1/20 0.44
POLB P06746 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
CASP2 P42575 1/20 0.41
ADRA1A P35348 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11173620 1.00 KDM4E (0.52) KDM4EMAPK1HIF1AALDH1A1SMN1; SMN2
SCHEMBL1839119 1.00 KDM4E (0.52) KDM4EMAPK1HIF1AALDH1A1SMN1; SMN2
SCHEMBL11180722 1.00 KDM4E (0.52) KDM4EMAPK1HIF1AALDH1A1SMN1; SMN2
SCHEMBL28560371 1.00 KDM4E (0.52) KDM4EMAPK1HIF1AALDH1A1SMN1; SMN2
SCHEMBL1837168 1.00 KDM4E (0.52) KDM4EMAPK1HIF1AALDH1A1SMN1; SMN2
SCHEMBL28622543 1.00 KDM4E (0.52) KDM4EMAPK1HIF1AALDH1A1SMN1; SMN2
SCHEMBL1837224 0.97 KDM4E (0.48) KDM4EMAPK1HIF1AALDH1A1SMN1; SMN2
SCHEMBL1309431 0.90 TDP1 (0.42) KDM4EMAPK1HIF1AALDH1A1SMN1; SMN2
SCHEMBL6278204 0.89 PAOX (0.64) KDM4EMAPK1HIF1AALDH1A1SMN1; SMN2
SCHEMBL6272996 0.89 PAOX (0.64) KDM4EMAPK1HIF1AALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12128119-B2 Essentially anhydrous hair-treatment compositions comprising a polyurethane latex polymer and bis-urea derivative L'OREAL (FR) 2024-10-29 US claimed
CN-118572064-A Silicon-carbon negative electrode material and preparation method and application thereof 碳一新能源集团有限责任公司 2024-08-30 CN claimed
US-20240238331-A1 COATINGS, FORMULATIONS, USES AND COATING METHODS BIOINTERACTIONS LTD (GB) 2024-07-18 US claimed
EP-4369935-A1 COATINGS, FORMULATIONS, USES AND COATING METHODS Biointeractions Ltd (GB) 2024-05-22 EP claimed
CN-117979826-A Coating, formulation, use and coating method 生物相互作用有限公司 2024-05-03 CN claimed
WO-2023151137-A1 OLED DISPLAY PANEL AND DISPLAY DEVICE 深圳市华星光电半导体显示技术有限公司 2023-08-17 WO claimed
WO-2023285840-A1 COATINGS, FORMULATIONS, USES AND COATING METHODS BIOINTERACTIONS LTD (GB) 2023-01-19 WO claimed
CN-114551758-A OLED display panel and display device 深圳市华星光电半导体显示技术有限公司 2022-05-27 CN claimed
US-10653610-B2 Essentially anhydrous hair-treatment compositions comprising a bis-urea derivative and silica aerogel L'OREAL (FR) 2020-05-19 US claimed
US-10555891-B2 Methods for treating chemically treated hair L'OREAL (FR) 2020-02-11 US claimed
EP-1711566-B1 UTILIZATION OF RADIOHARDENABLE RESINS BASED ON KETONE AND/OR UREA ALDEHYDE RESINS EVONIK DEGUSSA GMBH (DE) 2008-05-14 EP claimed
US-20080069949-A1 SILANE-FUNCTIONAL, CHLORINE-FREE COMPOSITION DEGUSSA GMBH (DE) 2008-03-20 US claimed
US-7329710-B2 Radiation-curable resins based on ketone-aldehyde and/or urea-aldehyde resins and a process for preparing them DEGUSSA AG (DE) 2008-02-12 US claimed
EP-1508581-B1 Radiation curable resins based on ketone and/or urea-aldehyde resins and process for their preparation DEGUSSA (DE) 2007-04-04 EP claimed
US-20050043501-A1 Radiation-curable resins based on ketone-aldehyde and/or urea-aldehyde resins and a process for preparing them DEGUSSA AG (DE) 2005-02-24 US claimed
US-6200683-B1 A RESIN BLEND OF TWO DIFFERENT POLYESTERS, AN AMINO RESIN CROSSLINKER, AN ACID CATALYST AND A UREA-ALDEHYDE CONDENSATE RESIN; HIGH SOLIDS; GLOSS; PROTECTIVE COATINGS; APPLIANCES; FURNITURE PPG INDUSTRIES OHIO, INC. 2001-03-13 US claimed
WO-1996018699-A1 COIL COATING COMPOSITIONS WITH LOW TEMPERATURE FLEXIBILITY AND IMPROVED STAIN RESISTANCE PPG INDUSTRIES, INC. (US) 1996-06-20 WO claimed
EP-0271776-B1 UREA-ALDEHYDE POLYCONDENSATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS BINDERS IN LACQUER COATINGS BASF Aktiengesellschaft (DE) 1992-06-03 EP claimed
EP-0408277-A2 Process for the preparation of aliphatic isocyanates ARCO CHEMICAL TECHNOLOGY, INC. (US) 1991-01-16 EP claimed
US-4906727-A Urea-aldehyde polycondensates, preparation thereof and use thereof as surface coating binders BASF AKTIENGESELLSCHAFT (DE) 1990-03-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240238331-A1 COATINGS, FORMULATIONS, USES AND COATING METHODS GNE, PUF60, HPSE KDM4E 2808/4885MAPK1 2335/4885HIF1A 1766/4885
US-12128119-B2 Essentially anhydrous hair-treatment compositions comprising a polyurethane latex polymer and bis-urea derivative UNG, SHH, SUCLG1 KDM4E 627/4885MAPK1 3379/4885HIF1A 1469/4885
US-10653610-B2 Essentially anhydrous hair-treatment compositions comprising a bis-urea derivative and silica aerogel FHIT, SUCLG1, SHH KDM4E 1233/4885MAPK1 4267/4885HIF1A 1304/4885
US-10555891-B2 Methods for treating chemically treated hair SHH, PLOD2, PLOD3 KDM4E 738/4885MAPK1 3820/4885HIF1A 1923/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.