⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6431334 | 0.83 | TP53 (0.33) | — | |
| SCHEMBL8581184 | 0.73 | — | — | |
| SCHEMBL13571691 | 0.69 | TP53 (0.33) | — | |
| SCHEMBL4884517 | 0.67 | — | — | |
| SCHEMBL18868373 | 0.65 | — | — | |
| SCHEMBL1479249 | 0.65 | — | — | |
| SCHEMBL15833158 | 0.65 | — | — | |
| SCHEMBL10250662 | 0.65 | — | — | |
| SCHEMBL8581183 | 0.65 | — | — | |
| SCHEMBL24500750 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12031179-B2 | Methods and compositions for reducing nucleotide impurities | Singular Genomics Systems, Inc. (US) | 2024-07-09 | — | — | US | disclosed |
| US-20230265505-A1 | METHODS AND COMPOSITIONS FOR REDUCING NUCLEOTIDE IMPURITIES | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-08-24 | — | — | US | disclosed |
| US-20230257414-A1 | NUCLEOTIDE ANALOGUES | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-08-17 | — | — | US | disclosed |
| US-20230242571-A1 | SILICON CONTAINING MODIFIED NUCLEOTIDE ANALOGS | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-08-03 | — | — | US | disclosed |
| US-20230203083-A1 | NUCLEOTIDE ANALOGUES | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-06-29 | — | — | US | disclosed |
| US-20230193361-A1 | METHODS AND COMPOSITIONS USEFUL FOR NUCLEIC ACID SEQUENCING | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-06-22 | — | — | US | disclosed |
| US-20230160001-A1 | NUCLEOTIDE CLEAVABLE LINKERS WITH RIGID SPACERS AND USES THEREOF | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-05-25 | — | — | US | disclosed |
| US-20080108557-A1 | Modified Proteins | NOVO NORDISK HEALTHCARE A/G (CH) | 2008-05-08 | — | — | US | disclosed |
| EP-1797192-A1 | MODIFIED PROTEINS | Novo Nordisk Health Care AG (CH) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006035057-A1 | MODIFIED PROTEINS | NOVO NORDISK HEALTH CARE AG (DK) | 2006-04-06 | — | — | WO | disclosed |