SCHEMBL6431334

SCHEMBL6431334

CC(C)C(=O)SSC(=O)C(C)C

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.33
MDM4 O15151 1/20 0.30
MDM2 Q00987 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4589315 0.83
SCHEMBL13571691 0.77 TP53 (0.33) TP53MDM4MDM2
SCHEMBL8581184 0.74
SCHEMBL4884517 0.74
SCHEMBL8581183 0.72
SCHEMBL15833158 0.72
SCHEMBL1479249 0.72
SCHEMBL18868373 0.72
SCHEMBL10250662 0.72
SCHEMBL10045204 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117122691-A Intelligent drug carrier with neighborhood effect and pH/reduction sensitive shell crosslinking, and preparation method and application thereof 华东理工大学 2023-11-28 CN claimed
CN-117122691-A Intelligent drug carrier with neighborhood effect and pH/reduction sensitive shell crosslinking, and preparation method and application thereof 华东理工大学 2023-11-28 CN disclosed
EP-1154771-A4 NITROSATED AND NITROSYLATED PROTON PUMP INHIBITORS, COMPOSITIONS AND METHODS OF USE NITROMED INC (US) 2005-04-20 EP disclosed
EP-1154771-A1 NITROSATED AND NITROSYLATED PROTON PUMP INHIBITORS, COMPOSITIONS AND METHODS OF USE Nitromed, Inc. (US) 2001-11-21 EP disclosed
EP-0626077-B1 IMAGE-RECORDING MATERIALS POLAROID CORP (US) 2001-11-21 EP disclosed
WO-2000050037-A1 NITROSATED AND NITROSYLATED PROTON PUMP INHIBITORS, COMPOSITIONS AND METHODS OF USE NITROMED, INC. (US) 2000-08-31 WO disclosed
EP-0606465-B1 THERMALLY DEVELOPABLE PHOTOSENSITIVE MATERIAL POLAROID CORP (US) 1999-02-17 EP disclosed
US-5430156-A Color photography POLAROID CORPORATION (US) 1995-07-04 US disclosed
US-5415970-A Thiazole dyes for silver halide images in color photography POLAROID CORPORATION (US) 1995-05-16 US disclosed
US-5414091-A Compounds for thermographic images using cyan dyes POLAROID CORPORATION (US) 1995-05-09 US disclosed
EP-0626077-A1 IMAGE-RECORDING MATERIALS POLAROID CORPORATION (US) 1994-11-30 EP disclosed
US-5340689-A For diffusion transfer color process POLAROID CORPORATION (US) 1994-08-23 US disclosed
EP-0606465-A1 THERMALLY DEVELOPABLE PHOTOSENSITIVE MATERIAL POLAROID CORPORATION (US) 1994-07-20 EP disclosed
WO-1994015256-A1 IMAGE-RECORDING MATERIALS POLAROID CORPORATION (US) 1994-07-07 WO disclosed
US-5319143-A Bis(aminoethanethiols) POLAROID CORPORATION (US) 1994-06-07 US disclosed
US-5316887-A Color-providing thiazolidine or tetrahydro-1,3-thiazine compounds, with reducing agent, thermal solvent, binder and silver halide POLAROID CORPORATION (US) 1994-05-31 US disclosed
WO-1994003835-A1 THERMALLY DEVELOPABLE PHOTOSENSITIVE MATERIAL POLAROID CORPORATION (US) 1994-02-17 WO disclosed
US-4853486-A Method for production of dithiodialdehyde NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) 1989-08-01 US disclosed
EP-0291521-A1 SULFUR-CONTAINING COMPOSITIONS, LUBRICANT, FUEL AND FUNCTIONAL FLUID COMPOSITIONS. LUBRIZOL CORP (US) 1988-11-23 EP disclosed
WO-1988003552-A2 SULFUR-CONTAINING COMPOSITIONS, LUBRICANT, FUEL AND FUNCTIONAL FLUID COMPOSITIONS THE LUBRIZOL CORPORATION (US) 1988-05-19 WO disclosed