Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 5/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10907052 | 1.00 | POLB (0.52) | POLBMMP2CYP2D6ALDH1A1KMT2A | |
| SCHEMBL9871468 | 1.00 | POLB (0.52) | POLBMMP2CYP2D6ALDH1A1KMT2A | |
| SCHEMBL10907053 | 1.00 | POLB (0.52) | POLBMMP2CYP2D6ALDH1A1KMT2A | |
| SCHEMBL8299354 | 0.88 | ALDH1A1 (0.59) | POLBMMP2CYP2D6ALDH1A1KMT2A | |
| SCHEMBL13708370 | 0.88 | ALDH1A1 (0.59) | POLBMMP2CYP2D6ALDH1A1KMT2A | |
| SCHEMBL1568318 | 0.86 | ALDH1A1 (0.61) | POLBMMP2CYP2D6ALDH1A1KMT2A | |
| SCHEMBL1568324 | 0.86 | ALDH1A1 (0.61) | POLBMMP2CYP2D6ALDH1A1KMT2A | |
| SCHEMBL9685718 | 0.86 | ALDH1A1 (0.61) | POLBMMP2CYP2D6ALDH1A1KMT2A | |
| SCHEMBL1568322 | 0.86 | ALDH1A1 (0.61) | POLBMMP2CYP2D6ALDH1A1KMT2A | |
| SCHEMBL4590383 | 0.85 | POLB (0.52) | POLBMMP2ALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008134035-A1 | ALPHA-UNSUBSTITUTED ARYLMETHYL PIPERAZINE PYRAZOLO[1,5-A] PYRIMIDINE AMIDE DERIVATIVES | PANACOS PHARMACEUTICALS, INC. (US) | 2008-11-06 | — | — | WO | disclosed |