SCHEMBL4590049

SCHEMBL4590049

O=C1CSC=CN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6348233 0.89
SCHEMBL6064791 0.75
SCHEMBL121144 0.72
SCHEMBL7640633 0.65
SCHEMBL6065013 0.65
SCHEMBL11315691 0.61
SCHEMBL12483162 0.59
SCHEMBL321826 0.58
SCHEMBL10369835 0.58
SCHEMBL1032769 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4103278-A1 SMALL MOLECULE STING ANTAGONISTS Curadev Pharma Pvt. Ltd. (IN) 2022-12-21 EP claimed
CN-104370853-B GSK-3 beta inhibitor or its salt and medicinal usage thereof 复旦大学 2016-08-10 CN claimed
CN-104370853-A GSK-3beta inhibitor or its salt and medicine application thereof UNIV FUDAN 2015-02-25 CN claimed
US-4179514-A INSECTICIDES, MITICIDES, NEMATOCIDES UNION CARBIDE CORPORATION (US) 1979-12-18 US claimed
US-20260001881-A1 COMPOUNDS AND METHODS FOR MODULATION OF G-PROTEIN-COUPLED RECEPTORS PRIMETIME LIFE SCIENCES LLC (US) 2026-01-01 US disclosed
WO-2024040009-A2 INHIBITORS OF METHIONINE AMINOPEPTIDASE-2 AND METHODS OF PREPARATION AND USES THEREOF PRIMETIME LIFE SCIENCES, LLC (US) 2024-02-22 WO disclosed
CN-112262145-B 2-aminopyrimidine derivative and preparation method and application thereof 上海奕拓医药科技有限责任公司 2023-08-01 CN disclosed
US-20230002389-A1 ADENINE ANALOGS, PRODRUGS, DERIVATIVES, COMPOSITIONS AND USES THEREOF PADIA JANAK KHIMCHAND (US) 2023-01-05 US disclosed
EP-4103278-A1 SMALL MOLECULE STING ANTAGONISTS Curadev Pharma Pvt. Ltd. (IN) 2022-12-21 EP disclosed
CN-115298176-A Compounds and their use in the treatment of bacterial infections 豪夫迈·罗氏有限公司 2022-11-04 CN disclosed
CN-115151304-A Small molecule interferon gene stimulating factor (STING) antagonists 库拉德夫制药私人有限公司 2022-10-04 CN disclosed
CN-114401969-A Heterocyclic compounds 豪夫迈·罗氏有限公司 2022-04-26 CN disclosed
US-4293501-A β-Lactam antibiotics, a process for their preparation and their use in pharmaceutical compositions BEECHAM GROUP LIMITED (GB) 1981-10-06 US disclosed
EP-0030392-A2 Intermediates for use in the preparation of carbapenems BEECHAM GROUP PLC (GB) 1981-06-17 EP disclosed
US-4255441-A β-Lactam antibiotics, a process for their prepaeration and their use in pharmaceutical compositions BEECHAM GROUP LIMITED (GB) 1981-03-10 US disclosed
EP-0019457-A2 Clavulanic acid derivatives, their preparation and pharmaceutical compositions BEECHAM GROUP PLC (GB) 1980-11-26 EP disclosed
US-4220727-A CARBOXYALKYL SILOXANES, ALIPHATIC GLYOXIMES, ARALKYL QUATERNARY AMMONIUM SALTS UNION CARBIDE CORPORATION (US) 1980-09-02 US disclosed
EP-0003740-A2 Beta-lactam antibiotics, a process for their preparation and pharmaceutical compositions containing them BEECHAM GROUP PLC (GB) 1979-09-05 EP disclosed
US-4111861-A ELASTOMERS UNION CARBIDE CORPORATION (US) 1978-09-05 US disclosed
US-4025625-A INHIBITORS OF THE ENZYME INDOLEAMINE-N-METHYL TRANSFERASE MERCK & CO., INC. (US) 1977-05-24 US disclosed