⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4590049 | 0.89 | — | — | |
| SCHEMBL6064791 | 0.67 | — | — | |
| SCHEMBL121144 | 0.64 | — | — | |
| SCHEMBL108935 | 0.61 | — | — | |
| SCHEMBL736481 | 0.59 | — | — | |
| SCHEMBL7640633 | 0.58 | — | — | |
| SCHEMBL6065013 | 0.58 | — | — | |
| SCHEMBL11315691 | 0.55 | — | — | |
| Hydrochloric Acid SCHEMBL31340495 | 0.55 | — | — | |
| SCHEMBL1781839 | 0.53 | HIF1A (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6960575-B2 | For use as inhibitors of chymase | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2005-11-01 | — | — | US | disclosed |
| US-20040097496-A1 | Novel thiazine derivatives | SANTEN PHARMACEUTICAL CO.,LTD. (JP) | 2004-05-20 | — | — | US | disclosed |