Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL8632177 | 0.94 | KDM1A (0.44) | KDM1AALDH1A1MAPT | |
| SCHEMBL80431 | 0.93 | KDM1A (0.45) | KDM1AMAPT | |
| Methane SCHEMBL7149466 | 0.91 | KDM1A (0.43) | KDM1AMAPT | |
| Methane SCHEMBL10447590 | 0.91 | KDM1A (0.43) | KDM1AMAPT | |
| SCHEMBL1556348 | 0.91 | KDM1A (0.43) | KDM1AMAPT | |
| SCHEMBL122872 | 0.89 | KDM1A (0.50) | KDM1AMAPT | |
| SCHEMBL1904517 | 0.89 | KDM1A (0.50) | KDM1AMAPT | |
| SCHEMBL235344 | 0.86 | KDM1A (0.48) | KDM1AMAPT | |
| SCHEMBL6682662 | 0.86 | KDM1A (0.48) | KDM1AMAPT | |
| SCHEMBL123151 | 0.86 | KDM1A (0.48) | KDM1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008134035-A1 | ALPHA-UNSUBSTITUTED ARYLMETHYL PIPERAZINE PYRAZOLO[1,5-A] PYRIMIDINE AMIDE DERIVATIVES | PANACOS PHARMACEUTICALS, INC. (US) | 2008-11-06 | — | — | WO | disclosed |
| WO-2008057420-A2 | EXTENDED TRITERPENE DERIVATIVES | PANACOS PHARMACEUTICALS, INC. (US) | 2008-05-15 | — | — | WO | disclosed |