Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4590084 | 0.94 | KDM1A (0.41) | KDM1AALDH1A1MAPT | |
| SCHEMBL5699292 | 0.94 | KDM1A (0.48) | KDM1AMAPTHSD11B1HDAC1HDAC2 | |
| SCHEMBL20552191 | 0.94 | KDM1A (0.48) | KDM1AMAPTHSD11B1HDAC1HDAC2 | |
| SCHEMBL693557 | 0.94 | KDM1A (0.48) | KDM1AMAPTHSD11B1HDAC1HDAC2 | |
| SCHEMBL235344 | 0.94 | KDM1A (0.48) | KDM1AMAPTHSD11B1HDAC1HDAC2 | |
| SCHEMBL8361882 | 0.94 | KDM1A (0.48) | KDM1AMAPTHSD11B1HDAC1HDAC2 | |
| SCHEMBL6682662 | 0.94 | KDM1A (0.48) | KDM1AMAPTHSD11B1HDAC1HDAC2 | |
| SCHEMBL1053630 | 0.94 | KDM1A (0.48) | KDM1AMAPTHSD11B1HDAC1HDAC2 | |
| SCHEMBL123151 | 0.94 | KDM1A (0.48) | KDM1AMAPTHSD11B1HDAC1HDAC2 | |
| SCHEMBL216035 | 0.94 | KDM1A (0.48) | KDM1AMAPTHSD11B1HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449015-B1 | Difluoromethyl compounds and liquid criystal medium | MERCK PATENT GMBH (DE) | 1998-07-01 | — | — | EP | disclosed |