Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | SUV39H2 | Q9H5I1 | 4/20 | 0.37 |
| ▸ | CKS1B | P61024 | 1/20 | 0.36 |
| ▸ | SKP1 | P63208 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10128141 | 0.76 | KCNA3 (0.46) | KCNA3DRD2CKS1BSKP1SKP2 | |
| SCHEMBL12746406 | 0.76 | KCNA3 (0.46) | KCNA3DRD2CKS1BSKP1SKP2 | |
| SCHEMBL4590519 | 0.75 | CNR1 (0.39) | — | |
| SCHEMBL3610965 | 0.75 | KCNA3 (0.38) | KCNA3DRD2KDM4DCCR5 | |
| SCHEMBL3610961 | 0.75 | KCNA3 (0.38) | KCNA3DRD2KDM4DCCR5 | |
| SCHEMBL3611264 | 0.75 | KCNA3 (0.38) | KCNA3DRD2KDM4DSUV39H2 | |
| SCHEMBL3602537 | 0.75 | SIGMAR1 (0.35) | MCHR1 | |
| SCHEMBL3615008 | 0.74 | KCNA3 (0.36) | KCNA3DRD2KDM4DCKS1BSKP1 | |
| SCHEMBL3609957 | 0.74 | KCNA3 (0.36) | KCNA3DRD2KDM4DCKS1BSKP1 | |
| SCHEMBL3618787 | 0.74 | KCNA3 (0.36) | KCNA3DRD2KDM4DCKS1BSKP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008120003-A1 | SUBSTITUTED PIPERIDINES FOR USE IN THE TREATMENT OF BACTERIAL INFECTIONS | ASTRAZENECA AB (SE) | 2008-10-09 | — | — | WO | disclosed |