Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 20/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4590094 | 0.91 | CTSS (0.81) | CTSS | |
| SCHEMBL4589901 | 0.90 | CTSS (0.62) | CTSS | |
| SCHEMBL4589749 | 0.89 | CTSS (0.61) | CTSS | |
| SCHEMBL4590155 | 0.89 | CTSS (0.61) | CTSS | |
| SCHEMBL4573672 | 0.87 | CTSS (1.00) | CTSS | |
| SCHEMBL4574415 | 0.84 | CTSS (1.00) | CTSS | |
| SCHEMBL4573674 | 0.81 | CTSS (0.98) | CTSS | |
| SCHEMBL5130779 | 0.81 | CTSS (1.00) | CTSS | |
| SCHEMBL4573587 | 0.80 | CTSS (1.00) | CTSS | |
| SCHEMBL4573577 | 0.80 | CTSS (1.00) | CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008100618-A2 | CARBON-LINKED TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S | SUNESIS PHARMACEUTICALS, INC. (US) | 2008-08-21 | — | — | WO | disclosed |