SCHEMBL4590438

SCHEMBL4590438

Cc1ccc(C(CCP(=O)(O)O)CCP(=O)(O)O)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.43
CA1 P00915 1/20 0.43
MMP8 P22894 1/20 0.43
LMNA P02545 2/20 0.42
TSHR P16473 1/20 0.42
CYP1A2 P05177 1/20 0.39
MMP2 P08253 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39
MAPT P10636 1/20 0.39
THRB P10828 1/20 0.39
PMP22 Q01453 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
GAA P10253 1/20 0.38
PGK1 P00558 2/20 0.38
PGK2 P07205 2/20 0.38
MEN1 O00255 1/20 0.37
ALDH1A1 P00352 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2173942 0.84 ACP3 (0.47) MMP8LMNACYP1A2CA14MAPT
SCHEMBL3885280 0.77 ALDH1A1 (0.47) CA12CA1MMP8LMNATSHR
SCHEMBL11524837 0.75 ESR1 (0.37) CA12CA9GAAMEN1KMT2A
SCHEMBL9619372 0.74 ALDH1A1 (0.44) CA12CA1MMP8LMNATSHR
SCHEMBL3883994 0.74 HTR2A (0.50) MEN1ALDH1A1KMT2A
SCHEMBL14183097 0.73 CHRNA7 (0.39) LMNASMN1; SMN2GAAALDH1A1ACHE
SCHEMBL16859932 0.73 ACP3 (0.58) CA12CA1MMP8LMNATSHR
P-Xylene SCHEMBL9064050 0.73 CHRNA7 (0.39) LMNASMN1; SMN2GAAALDH1A1ACHE
SCHEMBL1552133 0.73 SRC (0.60) CA12CA1MMP8LMNATSHR
SCHEMBL3883725 0.72 CA12 (0.46) CA12CA1MMP8LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1888706-B1 ORGANIC ELECTROLUMINESCENT DEVICE AND BORIC ACID AND BORINIC ACID DERIVATIVES USED THEREIN MERCK PATENT GMBH (DE) 2017-03-01 EP disclosed
EP-1888706-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND BORIC ACID AND BORINIC ACID DERIVATIVES USED THEREIN Merck Patent GmbH (DE) 2008-02-20 EP disclosed
WO-2006117052-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND BORIC ACID AND BORINIC ACID DERIVATIVES USED THEREIN MERCK PATENT GMBH (DE) 2006-11-09 WO disclosed