Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 9/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31213979 | 1.00 | MTNR1A (0.44) | MTNR1AMTNR1BCYP3A4TSHRKDM4E | |
| SCHEMBL28144519 | 0.81 | MTNR1A (0.41) | MTNR1AMTNR1BCYP3A4TSHRKDM4E | |
| SCHEMBL2701226 | 0.81 | MTNR1A (0.41) | MTNR1AMTNR1BCYP3A4TSHRKDM4E | |
| SCHEMBL28202807 | 0.81 | MTNR1A (0.41) | MTNR1AMTNR1BCYP3A4TSHRKDM4E | |
| SCHEMBL12719040 | 0.78 | KDM1A (0.44) | — | |
| SCHEMBL27999307 | 0.77 | MTNR1A (0.39) | MTNR1AMTNR1BCYP3A4TSHRKDM4E | |
| SCHEMBL7536358 | 0.75 | KDM1A (0.38) | MTNR1AMTNR1BALDH1A1OPRM1OPRK1 | |
| SCHEMBL29014216 | 0.75 | PDK2 (0.35) | MTNR1AOPRM1OPRK1OPRL1 | |
| SCHEMBL27778175 | 0.75 | TYMS (0.36) | TSHRKDM4EALDH1A1HPGDOPRM1 | |
| SCHEMBL28783256 | 0.75 | MEN1 (0.33) | MTNR1AMTNR1BCYP3A4TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104803881-B | Compound (2Z)-2-((4-bromophenyl) hydrazono-) acenaphthene-1-ketone and preparation method thereof and application | NANJING UNIVERSITY OF INFORMATION SCIENCE AND TECHNOLOGY (CN) | 2016-04-20 | — | — | CN | claimed |
| CN-103130211-B | The preparation method of Graphene | XIDIAN UNIVERSITY (CN) | 2015-10-21 | — | — | CN | claimed |
| CN-104803881-A | Compound (2Z)-2-((4-bromophenyl) hydrazono) acenaphthene-1-ketone as well as preparation method and application thereof | UNIV NANJING INF SCI & TECH | 2015-07-29 | — | — | CN | claimed |
| CN-103130211-A | Preparation method of graphene | UNIV XIDIAN | 2013-06-05 | — | — | CN | claimed |
| CN-113105475-B | Inhibitors of bruton's tyrosine kinase and methods of use thereof | 詹森药业有限公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-113105475-A | Inhibitors of bruton's tyrosine kinase and methods of use thereof | 詹森药业有限公司 | 2021-07-13 | — | — | CN | disclosed |
| CN-107533291-B | Compound, resist composition, and resist pattern formation method using same | 三菱瓦斯化学株式会社 | 2021-06-11 | — | — | CN | disclosed |
| CN-106957217-B | Polyhydric phenol compound for resist composition | 三菱瓦斯化学株式会社 | 2020-07-24 | — | — | CN | disclosed |
| CN-106995451-B | A kind of response type cysteine probe and preparation method thereof | 许昌学院 | 2019-03-15 | — | — | CN | disclosed |
| CN-107141303-B | A kind of response type sulfhydryl compound probe and preparation method thereof | 许昌学院 | 2019-03-15 | — | — | CN | disclosed |
| CN-109071563-A | Inhibitors of bruton's tyrosine kinase and methods of use thereof | 詹森药业有限公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-107090191-B | A kind of rhodamine fluorescent dyes and preparation method thereof | 许昌学院 | 2018-12-11 | — | — | CN | disclosed |
| EP-0967007-A2 | Method for microencapsulating a solid substance | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-12-29 | — | — | EP | disclosed |
| CN-1235866-A | Method for microencapsulating solid substance | SUMITOMO CHEMICAL CO (JP) | 1999-11-24 | — | — | CN | disclosed |
| CN-1191862-A | 8-substituted-1,3,8-triaza-spiro [4,5] decan-4-on derivatives | HOFFMANN LA ROCHE (CH) | 1998-09-02 | — | — | CN | disclosed |
| US-5254522-A | Pressure-sensitive or heat-sensitive recording material | CIBA-GEIGY CORPORATION (US) | 1993-10-19 | — | — | US | disclosed |
| EP-0196160-B1 | THERMOSETTING COMPOSITION, METHOD OF PRODUCING A FUSIBLE THERMOSETTING RESIN USING THIS COMPOSITION, AND PROCESS FOR THE PRODUCTION OF A CONDENSED, POLYNUCLEAR AROMATIC HYDROCARBON RESIN USING ONE OF THE COMPOSITIONS | Otani, Sugio (JP) | 1992-05-20 | — | — | EP | disclosed |
| EP-0453395-A1 | Pressure sensitive recording material | CIBA-GEIGY AG (CH) | 1991-10-23 | — | — | EP | disclosed |
| US-4758653-A | Thermosetting composition, method of producing fusible thermosetting resin using same, and process for the production of condensed, polynuclear aromatic hydrocarbon resin using same | FUJI STANDARD RESEARCH INC. (JP) | 1988-07-19 | — | — | US | disclosed |
| EP-0196160-A2 | Thermosetting composition, method of producing a fusible thermosetting resin using this composition, and process for the production of a condensed, polynuclear aromatic hydrocarbon resin using one of the compositions | Otani, Sugio (JP) | 1986-10-01 | — | — | EP | disclosed |