Sugi Predict

Sugi Predict / Compounds / Ocaperidone

Ocaperidone

Ocaperidone

SCHEMBL4590502

Cc1nc2c(C)cccn2c(=O)c1CCN1CCC(c2noc3cc(F)ccc23)CC1.O=C1CC[C@@H](C(=O)O)N1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SLC5A2

The experimentally established mechanism targets of Ocaperidone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DRD2 P14416 12/20 0.57
▸ HTR2A P28223 12/20 0.57
▸ HTR7 P34969 4/20 0.57
▸ KCNH2 Q12809 4/20 0.57
▸ HTR2C P28335 3/20 0.57
▸ HTR1A P08908 3/20 0.57
▸ ACHE P22303 3/20 0.57
▸ ADRA2A P08913 2/20 0.57
▸ ADRA2B P18089 2/20 0.57
▸ ADRA2C P18825 2/20 0.57
▸ DRD1 P21728 2/20 0.57
▸ DRD4 P21917 2/20 0.57
▸ DRD5 P21918 2/20 0.57
▸ HTR1D P28221 2/20 0.57
▸ HTR1B P28222 2/20 0.57
▸ ADRA1A P35348 2/20 0.57
▸ HRH1 P35367 2/20 0.57
▸ DRD3 P35462 2/20 0.57
▸ SCN5A Q14524 2/20 0.57
▸ SLC6A4 P31645 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ocaperidone SCHEMBL4590620 1.00 DRD2 (0.57) DRD2HTR2AHTR7KCNH2HTR2C
Ocaperidone SCHEMBL122321 0.90 DRD2 (0.66) DRD2HTR2AHTR7KCNH2HTR2C
Ocaperidone SCHEMBL29710913 0.90 DRD2 (0.66) DRD2HTR2AHTR7KCNH2HTR2C
Ocaperidone SCHEMBL4590337 0.89 HTR2A (0.61) DRD2HTR2AHTR7KCNH2HTR2C
Ocaperidone SCHEMBL4590606 0.88 HTR2A (0.59) DRD2HTR2AHTR7KCNH2HTR2C
Ocaperidone SCHEMBL4590272 0.87 DRD2 (0.59) DRD2HTR2AHTR7KCNH2HTR2C
Ocaperidone SCHEMBL4590338 0.87 HTR2A (0.58) DRD2HTR2AHTR7KCNH2HTR2C
Ocaperidone SCHEMBL4589820 0.86 DRD2 (0.56) DRD2HTR2AHTR7KCNH2HTR2C
Ocaperidone SCHEMBL4590515 0.84 HTR2A (0.56) DRD2HTR2AHTR7KCNH2HTR2C
Hydrochloric Acid SCHEMBL7298070 0.84 DRD2 (0.62) DRD2HTR2AHTR7KCNH2HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1888577-B1 OCAPERIDONE SALTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME JANSSEN PHARMACEUTICA NV (BE) 2008-11-12 — — EP disclosed
US-20080200479-A1 Ocaperidone Salts and Pharmaceutical Compositions Containing the Same NEURO3D S.A. (FR) 2008-08-21 — — US disclosed
EP-1888577-A1 OCAPERIDONE SALTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME JANSSEN PHARMACEUTICA N.V. (BE) 2008-02-20 — — EP disclosed
WO-2006090285-A1 OCAPERIDONE SALTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME JANSSEN PHARMACEUTICA N.V. (BE) 2006-08-31 — — WO disclosed
EP-1695973-A1 Ocaperidone salt and pharmaceutical compositions containing the same NEURO3D (FR) 2006-08-30 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080200479-A1 Ocaperidone Salts and Pharmaceutical Compositions Containing the Same OTC, PMP22, OLA1 DRD2 3175/4885HTR2A 3362/4885HTR7 3183/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.