Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16757065 | 0.95 | KMT2A (0.36) | GAARAD52KMT2ACHRNA7KCNH2 | |
| SCHEMBL25165704 | 0.92 | KMT2A (0.37) | GAARAD52KMT2AKCNH2 | |
| SCHEMBL8265735 | 0.92 | KMT2A (0.37) | GAARAD52KMT2AKCNH2 | |
| SCHEMBL30699749 | 0.92 | GAA (0.37) | GAARAD52KMT2A | |
| SCHEMBL3930544 | 0.90 | KMT2A (0.36) | GAARAD52KMT2AKCNH2 | |
| SCHEMBL553125 | 0.90 | KMT2A (0.36) | GAARAD52KMT2AKCNH2 | |
| SCHEMBL31441143 | 0.90 | KMT2A (0.36) | GAARAD52KMT2AKCNH2 | |
| SCHEMBL470816 | 0.90 | KMT2A (0.36) | GAARAD52KMT2A | |
| Hydrochloric Acid SCHEMBL1828960 | 0.87 | OPRM1 (0.35) | GAARAD52KMT2AKCNH2 | |
| SCHEMBL18796116 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345712-B1 | PYRROLIZINE DERIVATE AND ITS MANUFACTURE | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1992-10-07 | — | — | EP | claimed |
| EP-0345711-A2 | Process for the preparation of pyrrolizine derivatives | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1989-12-13 | — | — | EP | claimed |
| EP-0345712-A1 | Pyrrolizine derivate and its manufacture | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1989-12-13 | — | — | EP | claimed |
| JP-61229893-A | — | — | None | — | — | JP | disclosed |
| US-20260125384-A1 | INDAZOLE INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2026-05-07 | — | — | US | disclosed |
| EP-4387963-B1 | PHENYL- AND PYRIDOPYRAZOLE DERIVATIVES AS INHIBITORS OF DDR1 | REDX PHARMA LTD (GB) | 2025-12-24 | — | — | EP | disclosed |
| US-20250154156-A1 | QUINAZOLINE DERIVATIVE AS KRAS G12C MUTATION INHIBITOR | SHENZHEN FORWARD PHARMACEUTICALS CO., LIMITED (CN) | 2025-05-15 | — | — | US | disclosed |
| US-20250129021-A1 | SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS | Interdict Bio, Inc. (US) | 2025-04-24 | — | — | US | disclosed |
| WO-2025077825-A1 | METHODS AND COMPOSITIONS FOR TREATING CARDIO-PULMONARY DISORDERS | FAUNA BIO INCORPORATED (US) | 2025-04-17 | — | — | WO | disclosed |
| WO-2025064718-A1 | SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS | Interdict Bio, Inc. (US) | 2025-03-27 | — | — | WO | disclosed |
| WO-2024015262-A1 | FUSED RING KRAS INHIBITORS FOR TREATING DISEASE | BLOSSOMHILL THERAPEUTICS, INC. (US) | 2024-01-18 | — | — | WO | disclosed |
| US-4985569-A | Pyrrolizine derivative and its manufacture | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| US-4985569-A | Pyrrolizine derivative and its manufacture | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| US-4897495-A | Process for the preparation of pyrrolizine derivatives | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1990-01-30 | — | — | US | disclosed |
| EP-0345712-A1 | Pyrrolizine derivate and its manufacture | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1989-12-13 | — | — | EP | disclosed |
| EP-0345711-A2 | Process for the preparation of pyrrolizine derivatives | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1989-12-13 | — | — | EP | disclosed |
| US-4617401-A | ANTISPASMODIC AGENTS, VASODILATORS | SUNTORY LTD. (JP) | 1986-10-14 | — | — | US | disclosed |
| JP-S61229893-A | NOVEL ORGANOPLATINUM COMPLEX, PRODUCTION THEREOF, AND ANTITUMOR AGENT CONTAINING SAID COMPLEX AS ACTIVE COMPONENT | SANWA KAGAKU KENKYUSHO:KK | 1986-10-14 | — | — | JP | disclosed |
| EP-0039903-B1 | 8-SUBSTITUTED PYRROLIZIDINES AND QUATERNARY AMMONIUM SALTS THEREOF | SUNTORY KABUSHIKI KAISHA (JP) | 1986-04-09 | — | — | EP | disclosed |
| EP-0039903-A2 | 8-Substituted pyrrolizidines and quaternary ammonium salts thereof | SUNTORY KABUSHIKI KAISHA (JP) | 1981-11-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250129021-A1 | SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS | MYC, KRAS, NRAS | GAA 2022/4885RAD52 3080/4885KMT2A 1823/4885 |
| US-20260125384-A1 | INDAZOLE INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF | CGAS, GMPS, PRKG1 | GAA 163/4885RAD52 3246/4885KMT2A 4776/4885 |
| US-20250154156-A1 | QUINAZOLINE DERIVATIVE AS KRAS G12C MUTATION INHIBITOR | KRAS, NRAS, HRAS | GAA 1002/4885RAD52 2286/4885KMT2A 1979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.