Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 9/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | HTT | P42858 | 4/20 | 0.60 |
| ▸ | KDR | P35968 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.57 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.57 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.57 |
| ▸ | GSK3B | P49841 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989819 | 0.85 | FGFR1 (1.00) | FGFR1ALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL29357610 | 0.85 | FGFR1 (1.00) | FGFR1ALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL8006768 | 0.85 | FGFR1 (1.00) | FGFR1ALDH1A1SMN1; SMN2MAPTHTT | |
| Hydrochloric Acid SCHEMBL7986456 | 0.84 | FGFR1 (0.97) | FGFR1ALDH1A1SMN1; SMN2MAPTHTT | |
| Hydrochloric Acid SCHEMBL7989899 | 0.84 | FGFR1 (0.97) | FGFR1ALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL19848358 | 0.84 | FGFR1 (0.76) | FGFR1ALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL770591 | 0.81 | MAPT (0.66) | FGFR1ALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL14668371 | 0.81 | FGFR1 (0.67) | FGFR1ALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL3346179 | 0.79 | ALDH1A1 (1.00) | FGFR1ALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL15213062 | 0.79 | ALDH1A1 (0.70) | FGFR1ALDH1A1SMN1; SMN2MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107322-A1 | INDOLE, BENZIMIDAZOLE OR BENZOTRIAZOLE DERIVATIVES INCLUDING A PIPERIDINE OR PIPERAZINE CORE AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | disclosed |