Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.56 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 3/20 | 0.43 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4590988 | 1.00 | TRPV1 (0.56) | TRPV1RIPK1MEN1NPC1RAB9A | |
| SCHEMBL4591089 | 1.00 | TRPV1 (0.56) | TRPV1RIPK1MEN1NPC1RAB9A | |
| SCHEMBL14082150 | 0.91 | MEN1 (0.56) | TRPV1RIPK1MEN1NPC1RAB9A | |
| SCHEMBL14083033 | 0.87 | USP30 (0.45) | TRPV1MAPK14SMYD3 | |
| SCHEMBL14082149 | 0.86 | TRPV1 (0.54) | TRPV1RIPK1MEN1NPC1RAB9A | |
| SCHEMBL14082136 | 0.85 | TRPV1 (0.53) | TRPV1RIPK1MEN1NPC1RAB9A | |
| SCHEMBL6364617 | 0.85 | TRPV1 (0.58) | TRPV1RIPK1MEN1NPC1RAB9A | |
| SCHEMBL14082757 | 0.83 | NTRK1 (0.46) | TRPV1 | |
| SCHEMBL14082798 | 0.83 | RORC (0.46) | MAPK14HPGDS | |
| SCHEMBL14082153 | 0.83 | PIM1 (0.52) | TRPV1RIPK1MEN1KMT2ATRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664041-B1 | PHENYL-CARBOXAMIDE COMPOUNDS USEFUL FOR TREATING PAIN | EURO CELTIQUE SA (LU) | 2008-07-02 | — | — | EP | claimed |