Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 6/20 | 0.47 |
| ▸ | TUBB | P07437 | 6/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 6/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 6/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 6/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 6/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 6/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 6/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 6/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 6/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 6/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 6/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 8/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4576964 | 0.95 | LCK (0.53) | LCKBCHETUBB4ATUBBTUBA3C | |
| SCHEMBL4577384 | 0.95 | LCK (0.61) | LCKBCHETUBB4ATUBBTUBA3C | |
| SCHEMBL5351438 | 0.82 | LMNA (0.53) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5351444 | 0.82 | LMNA (0.63) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5037713 | 0.82 | LCK (0.56) | LCKBCHETUBB4ATUBBTUBA3C | |
| SCHEMBL31370470 | 0.81 | LCK (0.53) | LCKBCHETUBB4ATUBBTUBA3C | |
| SCHEMBL7493013 | 0.80 | LCK (0.50) | LCKBCHETUBB4ATUBBTUBA3C | |
| SCHEMBL13609711 | 0.80 | BCHE (0.69) | LCKBCHELMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL6784411 | 0.80 | LCK (0.57) | LCKBCHETUBB4ATUBBTUBA3C | |
| SCHEMBL12393042 | 0.80 | LCK (0.57) | LCKBCHETUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7435744-B2 | Piperidine derivatives as NMDA receptor antagonists | GEDEON RICHTER VEGYESZETI GYAR RT (HU) | 2008-10-14 | — | — | US | disclosed |
| US-20040157886-A1 | Piperdine derivatives as NMDA receptor antagonists | UCB Biopharma SRL (BE) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157886-A1 | Piperdine derivatives as NMDA receptor antagonists | GRIN1, GRIN2D, GRIN2C | LCK 2183/4885BCHE 1787/4885TUBB4A 2853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.