Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 20/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 16/20 | 0.70 |
| ▸ | SLC6A5 | Q9Y345 | 10/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8206908 | 0.90 | SLC6A9 (0.64) | SLC6A9KCNH2SLC6A5CYP2D6CYP3A4 | |
| SCHEMBL8206943 | 0.89 | SLC6A9 (0.71) | SLC6A9KCNH2SLC6A5CYP2D6CYP3A4 | |
| SCHEMBL375306 | 0.87 | SLC6A9 (0.75) | SLC6A9KCNH2SLC6A5CYP2D6CYP3A4 | |
| SCHEMBL8213349 | 0.87 | SLC6A9 (0.75) | SLC6A9KCNH2SLC6A5CYP2D6CYP3A4 | |
| SCHEMBL8220122 | 0.87 | SLC6A9 (0.74) | SLC6A9KCNH2SLC6A5CYP2D6CYP3A4 | |
| SCHEMBL4574803 | 0.86 | SLC6A9 (0.76) | SLC6A9KCNH2SLC6A5CYP2D6CYP3A4 | |
| SCHEMBL8216023 | 0.85 | SLC6A9 (0.75) | SLC6A9KCNH2SLC6A5CYP2D6CYP3A4 | |
| SCHEMBL4591106 | 0.85 | SLC6A9 (0.71) | SLC6A9KCNH2SLC6A5CYP2D6CYP3A4 | |
| SCHEMBL8213721 | 0.84 | SLC6A9 (0.67) | SLC6A9KCNH2SLC6A5CYP2D6CYP3A4 | |
| SCHEMBL8218475 | 0.84 | SLC6A9 (0.71) | SLC6A9KCNH2SLC6A5CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008065500-A2 | HETEROARYL AMIDES AS TYPE I GLYCINE TRANSPORT INHIBITORS | PFIZER PRODUCTS INC. (US) | 2008-06-05 | — | — | WO | disclosed |