Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8246488 | 0.88 | ADORA2A (0.60) | ADORA2AITK | |
| SCHEMBL4590235 | 0.88 | ADORA2A (0.86) | ADORA2AITK | |
| SCHEMBL4590765 | 0.87 | ADORA2A (0.86) | ADORA2AITK | |
| SCHEMBL14156154 | 0.87 | ADORA2A (1.00) | ADORA2AITK | |
| SCHEMBL4590427 | 0.86 | ADORA2A (0.80) | ADORA2A | |
| SCHEMBL4589421 | 0.85 | ADORA2A (0.73) | ADORA2A | |
| SCHEMBL4590205 | 0.85 | ADORA2A (0.76) | ADORA2A | |
| SCHEMBL14156039 | 0.85 | ADORA2A (1.00) | ADORA2AITK | |
| SCHEMBL4589290 | 0.84 | ADORA2A (0.57) | ADORA2A | |
| SCHEMBL14156187 | 0.83 | ADORA2A (0.79) | ADORA2AITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080146536-A1 | 2-Aminoimidazopyridines for treating neurodegenerative diseases | PHARMACOPEIA, INC. (US) | 2008-06-19 | — | — | US | disclosed |
| US-20080146536-A1 | 2-Aminoimidazopyridines for treating neurodegenerative diseases | PHARMACOPEIA, INC. (US) | 2008-06-19 | — | — | US | disclosed |
| US-20080146536-A1 | 2-Aminoimidazopyridines for treating neurodegenerative diseases | PHARMACOPEIA, INC. (US) | 2008-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146536-A1 | 2-Aminoimidazopyridines for treating neurodegenerative diseases | ADORA2A, ADORA1, ADORA3 | ADORA2A 1/4885ITK 3770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.