Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | PDE5A | O76074 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4498181 | 0.92 | TYK2 (0.56) | TYK2ALDH1A1PDE5ATSHRL3MBTL1 | |
| SCHEMBL4510623 | 0.91 | TYK2 (0.55) | TYK2ALDH1A1PDE5ATSHRL3MBTL1 | |
| SCHEMBL17506173 | 0.90 | TYK2 (0.57) | TYK2ALDH1A1PDE5ATSHRL3MBTL1 | |
| SCHEMBL4510202 | 0.87 | TYK2 (0.58) | TYK2ALDH1A1PDE5ATSHRL3MBTL1 | |
| SCHEMBL4512357 | 0.86 | KMT2A (0.53) | TYK2ALDH1A1PDE5ATSHRL3MBTL1 | |
| SCHEMBL4502011 | 0.86 | MAPK1 (0.50) | TYK2ALDH1A1TSHRHPGDTP53 | |
| Hydrochloric Acid SCHEMBL4511418 | 0.85 | TYK2 (0.62) | TYK2ALDH1A1PDE5ATSHRL3MBTL1 | |
| SCHEMBL4501740 | 0.85 | ALDH1A1 (0.52) | TYK2ALDH1A1PDE5ATSHRL3MBTL1 | |
| SCHEMBL4504690 | 0.85 | TYK2 (0.49) | TYK2ALDH1A1PDE5ATSHRL3MBTL1 | |
| SCHEMBL4513652 | 0.84 | TYK2 (0.50) | TYK2ALDH1A1PDE5ATSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008055959-A1 | NOVEL COMPOUNDS USEFUL FOR THE TREATMENT OF DEGENERATIVE & INFLAMMATORY DISEASES | GALAPAGOS N.V. (BE) | 2008-05-15 | — | — | WO | claimed |