SCHEMBL4591220

SCHEMBL4591220

O=C(O)c1ccc(C(=O)O)c(C(O)C=CO)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACE2 Q9BYF1 2/20 0.43
KDM4E B2RXH2 2/20 0.41
MYC P01106 1/20 0.38
PTPN1 P18031 1/20 0.37
L3MBTL1 Q9Y468 3/20 0.36
POLB P06746 2/20 0.36
MAPT P10636 2/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
GAA P10253 1/20 0.36
CA4 P22748 1/20 0.36
CA6 P23280 1/20 0.36
PTGS2 P35354 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
TSHR P16473 3/20 0.35
TP53 P04637 1/20 0.35
CDC25A P30304 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL788898 0.81 ACE2 (0.44) ACE2KDM4EMYCPTPN1L3MBTL1
SCHEMBL27729860 0.78 ACE2 (0.50) ACE2KDM4EMYCPTPN1L3MBTL1
SCHEMBL4577143 0.75 ACE2 (0.56) ACE2KDM4EMYCPTPN1L3MBTL1
SCHEMBL6049245 0.75 ACE2 (0.47) ACE2KDM4EMYCPTPN1L3MBTL1
SCHEMBL16115781 0.75 ACE2 (0.56) ACE2KDM4EMYCPTPN1L3MBTL1
SCHEMBL1356407 0.73 ACE2 (0.67) ACE2KDM4EMYCPTPN1L3MBTL1
SCHEMBL8373539 0.73 ACE2 (0.49) ACE2KDM4EMYCPTPN1L3MBTL1
SCHEMBL14122795 0.73 ACE2 (0.49) ACE2KDM4EMYCPTPN1L3MBTL1
SCHEMBL8382167 0.73 ACE2 (0.49) ACE2KDM4EMYCPTPN1L3MBTL1
SCHEMBL815099 0.72 ACE2 (0.51) ACE2KDM4EMYCPTPN1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7390869-B2 demetallization of polymerization catalysts in the process of producing polyester, prevent packaging made from polyesters to appear hazy, yellowing; absorption with a non-catalytic porous carbon material in the presence of hydrogen; purification EASTMAN CHEMICAL COMPANY (US) 2008-06-24 US claimed
EP-1899408-A2 PROCESS FOR REMOVING METAL SPECIES IN THE PRESENCE OF HYDROGEN AND A POROUS MATERIAL AND POLYESTER POLYMER CONTAINING REDUCED AMOUNTS OF METAL SPECIES EASTMAN CHEMICAL COMPANY (US) 2008-03-19 EP claimed
WO-2006138031-A2 PROCESS FOR REMOVING METAL SPECIES IN THE PRESENCE OF HYDROGEN AND A POROUS MATERIAL AND POLYESTER POLYMER CONTAINING REDUCED AMOUNTS OF METAL SPECIES EASTMAN CHEMICAL COMPANY (US) 2006-12-28 WO claimed
US-20060278039-A1 demetallization of polymerization catalysts in the process of producing polyester, prevent packaging made from polyesters to appear hazy, yellowing; absorption with a non-catalytic porous carbon material in the presence of hydrogen; purification ALPEK POLYESTER, S.A. DE C.V. (MX) 2006-12-14 US claimed
US-8921509-B2 Process for removing metal species in the presence of hydrogen and a porous material and polyester polymer containing reduced amounts of metal species GRUPO PETROTEMEX, S.A. DE C.V. (MX) 2014-12-30 US disclosed
US-8530609-B2 Process for removing metal species in the presence of hydrogen and a porous material and polyester polymer containing reduced amounts of metal species GRUPO PETROTEMEX, S.A. DE C.V. (MX) 2013-09-10 US disclosed
US-20120253004-A1 PROCESS FOR REMOVING METAL SPECIES IN THE PRESENCE OF HYDROGEN AND A POROUS MATERIAL AND POLYESTER POLYMER CONTAINING REDUCED AMOUNTS OF METAL SPECIES GRUPO PETROTEMEX, S.A. DE C.V. (MX) 2012-10-04 US disclosed
US-20080194750-A1 aromatic polyesters having low concentrations of antimony, germanium, cobalt, titanium, zinc, manganese, calcium and magnesium EASTMAN CHEMICAL COMPANY (US) 2008-08-14 US disclosed
US-7390869-B2 demetallization of polymerization catalysts in the process of producing polyester, prevent packaging made from polyesters to appear hazy, yellowing; absorption with a non-catalytic porous carbon material in the presence of hydrogen; purification EASTMAN CHEMICAL COMPANY (US) 2008-06-24 US disclosed
US-20060278039-A1 demetallization of polymerization catalysts in the process of producing polyester, prevent packaging made from polyesters to appear hazy, yellowing; absorption with a non-catalytic porous carbon material in the presence of hydrogen; purification ALPEK POLYESTER, S.A. DE C.V. (MX) 2006-12-14 US disclosed