SCHEMBL815099

SCHEMBL815099

O=C(O)c1ccc(C(=O)O)c(C(O)CO)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACE2 Q9BYF1 4/20 0.51
KDM4E B2RXH2 2/20 0.43
RARB P10826 1/20 0.42
RARG P13631 1/20 0.42
MYC P01106 1/20 0.40
PTPN1 P18031 1/20 0.39
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
CA4 P22748 1/20 0.38
CA6 P23280 1/20 0.38
PTGS2 P35354 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TSHR P16473 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isophthalic Acid SCHEMBL6478546 0.94 ACE2 (0.47) ACE2KDM4ERARBRARGMYC
SCHEMBL2725195 0.86 ACE2 (0.46) ACE2KDM4EMYCPTPN1CA12
SCHEMBL1298535 0.85 ACE2 (0.44) ACE2KDM4EMYCPTPN1CA12
SCHEMBL7524968 0.84 ACE2 (0.47) ACE2KDM4EMYCPOLBGAA
SCHEMBL21143412 0.83 ACE2 (0.43) ACE2KDM4ERARBMYCPTPN1
SCHEMBL21143417 0.82 ACE2 (0.43) ACE2KDM4ERARBMYCPTPN1
SCHEMBL4541962 0.82 ACE2 (0.40) ACE2KDM4ERARBRARGMAPT
SCHEMBL5685962 0.81 ACE2 (0.45) ACE2KDM4EMYCTSHRTP53
SCHEMBL31315029 0.81 ACE2 (0.49) ACE2KDM4EMYCPOLBTSHR
SCHEMBL27729860 0.81 ACE2 (0.50) ACE2KDM4EMYCPTPN1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10884348-B2 Electrophotographic photoreceptor, and electrophotographic cartridge and image forming apparatus including same MITSUBISHI CHEMICAL CORPORATION (JP) 2021-01-05 US disclosed
US-20190219938-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND ELECTROPHOTOGRAPHIC CARTRIDGE AND IMAGE FORMING APPARATUS INCLUDING SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2019-07-18 US disclosed
US-8063122-B2 Mixture, polyester composition, film and procedures for their manufacture LURGI ZIMMER GMBH (DE) 2011-11-22 US disclosed
US-20060069184-A1 Mixture, polyester composition, film and procedures for their manufacture ZIMMER AG (DE) 2006-03-30 US disclosed
US-6451430-B1 CHEMICAL POLYMERIZATION ADHESIVE BOND BETWEEN THE SURFACES POLYURETHANE FOAM LAYER HAVING BONDED, FREE, UNREACTED, ETHYLENICALLY UNSATURATED GROUPS LIKE ALLYL OR ACRYLIC GROUPS; UNSATURATED POLYESTER HEHR INTERNATIONAL INC. 2002-09-17 US disclosed
EP-0895487-A4 MODIFIED RIGID, FOAMABLE URETHANE COMPOSITION AND METHOD HEHR INTERNATIONAL INC (US) 1999-06-30 EP disclosed
EP-0895487-A1 MODIFIED RIGID, FOAMABLE URETHANE COMPOSITION AND METHOD Hehr International Inc. (US) 1999-02-10 EP disclosed
WO-1997039836-A1 MODIFIED RIGID, FOAMABLE URETHANE COMPOSITION AND METHOD HEHR INTERNATIONAL INC. (US) 1997-10-30 WO disclosed