⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8206020 | 0.71 | — | — | |
| SCHEMBL2192231 | 0.71 | — | — | |
| SCHEMBL724735 | 0.63 | — | — | |
| SCHEMBL18285 | 0.63 | — | — | |
| SCHEMBL28524 | 0.63 | — | — | |
| Water SCHEMBL1290581 | 0.58 | ALDH1A1 (0.83) | — | |
| SCHEMBL10355929 | 0.58 | — | — | |
| Ammonia Solution, Strong SCHEMBL20567139 | 0.58 | — | — | |
| Bromide SCHEMBL22773716 | 0.58 | — | — | |
| Water SCHEMBL620210 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 267 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3725339-B1 | ABSORBABLE IRON-BASED IMPLANTABLE DEVICE | BIOTYX MEDICAL SHENZHEN CO LTD (CN) | 2024-01-24 | — | — | EP | claimed |
| CN-115943307-A | MR1 ligands and pharmaceutical compositions for immunomodulation | 巴塞尔大学 | 2023-04-07 | — | — | CN | claimed |
| US-20230099822-A1 | MR1 LIGANDS AND PHARMACEUTICAL COMPOSITIONS FOR IMMUNOMODULATION | UNIVERSITÄT BASEL (CH) | 2023-03-30 | — | — | US | claimed |
| EP-3889602-A1 | MR1 LIGANDS AND PHARMACEUTICAL COMPOSITIONS FOR IMMUNOMODULATION | Universität Basel (CH) | 2021-10-06 | — | — | EP | claimed |
| WO-2021144475-A1 | MR1 LIGANDS AND PHARMACEUTICAL COMPOSITIONS FOR IMMUNOMODULATION | UNIVERSITÄT BASEL (CH) | 2021-07-22 | — | — | WO | claimed |
| US-20210187170-A1 | ABSORBABLE IRON-BASED IMPLANTABLE DEVICE | BIOTYX MEDICAL (SHENZHEN) CO., LTD. (CN) | 2021-06-24 | — | — | US | claimed |
| EP-3725339-A1 | ABSORBABLE IRON-BASED IMPLANTABLE DEVICE | Lifetech Scientific (Shenzhen) Co., Ltd (CN) | 2020-10-21 | — | — | EP | claimed |
| US-8242175-B2 | Class of histone deacetylase inhibitors | DAC S.R.L. (IT) | 2012-08-14 | — | — | US | claimed |
| US-20110077247-A1 | CLASS OF HISTONE DEACETYLASE INHIBITORS | DAC S.r.I. (IT) | 2011-03-31 | — | — | US | claimed |
| EP-2049508-B1 | N-HYDROXY-3-(4-{3-PHENYL-3-OXO-PROPENYL}-PHENYL)-ACRYLAMIDE DERIVATIVES AND RELATED COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS FOR THE TREATMENT OF CANCER | DAC SRL (IT) | 2010-06-09 | — | — | EP | claimed |
| US-20100113438-A1 | CLASS OF HISTONE DEACETYLASE INHIBITORS | DAC S.R.L. (IT) | 2010-05-06 | — | — | US | claimed |
| CN-101448802-A | N-hydroxy-3-(4-{3-phenyl-S-oxo-propenyl}-phenyl)-acrylamide derivatives and related compounds as histone deacetylase inhibitors for the treatment of cancer | DAC SRL (IT) | 2009-06-03 | — | — | CN | claimed |
| EP-2049508-A2 | N-HYDROXY-3-(4-{3-PHENYL-3-OXO-PROPENYL}-PHENYL)-ACRYLAMIDE DERIVATIVES AND RELATED COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS FOR THE TREATMENT OF CANCER | DAC S.r.l. (IT) | 2009-04-22 | — | — | EP | claimed |
| WO-2007113249-A2 | N-HYDROXY-3-(4-{3-PHENYL-S-OXO-PROPENYL}-PHENYL)-ACRYLAMIDE DERIVATIVES AND RELATED COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS FOR THE TREATMENT OF CANCER | DAC S.R.L. (IT) | 2007-10-11 | — | — | WO | claimed |
| US-20050165052-A1 | Substituted quinolines for the treatment of protozoa and retrovirus co-infections | INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (FR) | 2005-07-28 | — | — | US | claimed |
| WO-2000051708-A1 | POLYESTER WATER-BASED DEFOAMER | VULCAN PERFORMANCE CHEMICALS (US) | 2000-09-08 | — | — | WO | claimed |
| EP-0099017-B1 | PHENYL-ACETIC-ACID DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSTIONS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1988-03-02 | — | — | EP | claimed |
| US-4209450-A | Introduction of a carbonyl group into a cyclohexene ring | BASK AKTIENGESELLSCHAFT (DE) | 1980-06-24 | — | — | US | claimed |
| CN-118284639-A | Latent curing agent, process for producing the same, and curable composition | 迪睿合株式会社 | 2024-07-02 | — | — | CN | disclosed |
| US-4016184-A | PROSTAGLANDINS, BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1977-04-05 | — | — | US | disclosed |