⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL932700 | 0.92 | — | — | |
| SCHEMBL85991 | 0.92 | — | — | |
| SCHEMBL27942585 | 0.88 | — | — | |
| Potassium SCHEMBL30087616 | 0.88 | — | — | |
| Methylamine SCHEMBL27082389 | 0.85 | — | — | |
| SCHEMBL14320818 | 0.81 | TTR (0.43) | — | |
| SCHEMBL10187695 | 0.77 | — | — | |
| SCHEMBL1060050 | 0.77 | — | — | |
| SCHEMBL326285 | 0.77 | — | — | |
| Tetrahydrofuran SCHEMBL10705246 | 0.76 | ALDH1A1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247725-A1 | PROCESS FOR PREPARING SOLKETAL ACRYLATE BY TRANSESTERIFICATION | BASF SE (DE) | 2023-12-28 | — | — | WO | disclosed |
| US-20230330047-A1 | DISPERSIBLE FORMULATIONS OF N-((R)-2,3-DIHYDROXYPROPOXY)-3,4-DIFLUORO-2-(2- FLUORO-4-IODO-PHENYLAMINO)-BENAZMIDE AND USES THEREOF | SPRINGWORKS THERAPEUTICS, INC. (US) | 2023-10-19 | — | — | US | disclosed |
| EP-3603398-A1 | AGROCHEMICAL COMPOSITION AND METHODS OF PREPARING AND USING THE SAME | RHODIA OPERATIONS (FR) | 2020-02-05 | — | — | EP | disclosed |
| EP-1556078-A4 | METHODS FOR TREATING LUNG CANCER USING INSULIN-LIKE GROWTH FACTORBINDING PROTEIN-3 | INSMED INC (US) | 2008-01-09 | — | — | EP | disclosed |
| EP-1556078-A1 | METHODS FOR TREATING LUNG CANCER USING INSULIN-LIKE GROWTH FACTORBINDING PROTEIN-3 | Insmed, Inc. (US) | 2005-07-27 | — | — | EP | disclosed |
| US-20040127411-A1 | Methods for treating lung cancer using insulin-like growth factor binding protein-3 | INSMED, INC. | 2004-07-01 | — | — | US | disclosed |
| WO-2004024179-A1 | METHODS FOR TREATING LUNG CANCER USING INSULIN-LIKE GROWTH FACTORBINDING PROTEIN-3 | INSMED, INC. (US) | 2004-03-25 | — | — | WO | disclosed |