Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 5/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28806264 | 0.92 | PTGDR2 (0.44) | APEX1KDM4EHSD17B10ALDH1A1MAPK1 | |
| SCHEMBL29003855 | 0.90 | HTR2C (0.51) | APEX1NOTUM | |
| SCHEMBL16962726 | 0.83 | TDP1 (0.39) | NOTUMTDP1MEN1KMT2AGAA | |
| SCHEMBL28353746 | 0.81 | MEN1 (0.51) | KDM4EHSD17B10ALDH1A1HPGDPOLB | |
| SCHEMBL39857 | 0.80 | ALDH1A1 (0.55) | APEX1KDM4EHSD17B10ALDH1A1MAPK1 | |
| SCHEMBL11675296 | 0.80 | PTGDR2 (0.44) | NOTUMKDM4EHSD17B10ALDH1A1MAPK1 | |
| SCHEMBL27925249 | 0.78 | TDP1 (0.42) | TDP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL699717 | 0.78 | ALDH1A1 (0.53) | APEX1KDM4EHSD17B10ALDH1A1MAPK1 | |
| SCHEMBL16958770 | 0.78 | TDP1 (0.36) | NOTUMKDM4ETDP1MEN1KMT2A | |
| SCHEMBL4969775 | 0.77 | NOTUM (0.49) | NOTUMKDM4EHSD17B10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893603-A1 | PIPERIDIN-4-YL-AMIDE DERIVATIVES AND THEIR USE AS SST RECEPTOR SUBTYPE 5 ANTAGONISTS | F. Hoffmann-La Roche AG (CH) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006128803-A1 | PIPERIDIN-4-YL-AMIDE DERIVATIVES AND THEIR USE AS SST RECEPTOR SUBTYPE 5 ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-12-07 | — | — | WO | disclosed |