Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.49 |
| ▸ | FES | P07332 | 1/20 | 0.49 |
| ▸ | RET | P07949 | 1/20 | 0.49 |
| ▸ | MARK3 | P27448 | 1/20 | 0.49 |
| ▸ | TYK2 | P29597 | 1/20 | 0.49 |
| ▸ | FLT4 | P35916 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25784651 | 0.90 | HDAC2 (0.61) | RECQLHDAC8HDAC2HDAC6SMN1; SMN2 | |
| SCHEMBL2755854 | 0.87 | RECQL (0.71) | RECQLHDAC8HDAC2HDAC6SMN1; SMN2 | |
| SCHEMBL25784780 | 0.84 | SMN1; SMN2 (0.64) | RECQLHDAC8HDAC2HDAC6SMN1; SMN2 | |
| SCHEMBL25779421 | 0.84 | RECQL (0.76) | RECQLSMN1; SMN2KMT2ACYP1A2CYP3A4 | |
| SCHEMBL26936154 | 0.83 | CYP1A2 (0.55) | RECQLHDAC8HDAC2HDAC6SMN1; SMN2 | |
| SCHEMBL3558312 | 0.82 | MEN1 (0.63) | RECQLHDAC8HDAC2HDAC6SMN1; SMN2 | |
| SCHEMBL30208757 | 0.82 | MEN1 (0.63) | RECQLHDAC8HDAC2HDAC6SMN1; SMN2 | |
| SCHEMBL26936166 | 0.82 | HDAC2 (0.53) | RECQLHDAC8HDAC2HDAC6SMN1; SMN2 | |
| SCHEMBL4462450 | 0.81 | HDAC8 (0.56) | RECQLHDAC8HDAC2HDAC6SMN1; SMN2 | |
| SCHEMBL23222377 | 0.81 | HDAC2 (0.58) | RECQLHDAC8HDAC2HDAC6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114272388-A | Composite material based on two-dimensional nano carbon sheet and preparation and application thereof | 华中科技大学 | 2022-04-05 | — | — | CN | disclosed |
| EP-1673085-A4 | C-MET MODULATORS AND METHODS OF USE | EXELIXIS INC (US) | 2008-12-10 | — | — | EP | disclosed |
| EP-1673085-A2 | C-MET MODULATORS AND METHODS OF USE | Exelixis, Inc. (US) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005030140-A2 | C-MET MODULATORS AND METHODS OF USE | EXELIXIS, INC. (US) | 2005-04-07 | — | — | WO | disclosed |