Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | HCK | P08631 | 1/20 | 0.42 |
| ▸ | ROS1 | P08922 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL180781 | 1.00 | DGAT1 (0.61) | DGAT1NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL180744 | 0.98 | DGAT1 (0.61) | DGAT1NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL180521 | 0.80 | DGAT1 (0.71) | DGAT1NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL181064 | 0.78 | DGAT1 (0.54) | DGAT1NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL181063 | 0.78 | DGAT1 (0.54) | DGAT1NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL180569 | 0.77 | DGAT1 (0.55) | DGAT1NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL180568 | 0.77 | DGAT1 (0.55) | DGAT1NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL180660 | 0.76 | DGAT1 (1.00) | DGAT1NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL180780 | 0.76 | DGAT1 (0.66) | DGAT1NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL12203212 | 0.75 | DGAT1 (0.51) | DGAT1NPC1RAB9AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004607-A2 | NEW COMPOUNDS | Novartis AG (CH) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007126957-A2 | NEW COMPOUNDS | NOVARTIS AG (CH) | 2007-11-08 | — | — | WO | disclosed |