Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.54 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.54 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.54 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29561761 | 0.79 | HTT (0.69) | P2RX1MAPTMEN1HTTKMT2A | |
| SCHEMBL16670141 | 0.79 | HTT (0.69) | P2RX1MAPTMEN1HTTKMT2A | |
| SCHEMBL4683413 | 0.75 | KCNK3 (0.88) | P2RX1MAPTMEN1HTTKMT2A | |
| SCHEMBL5595455 | 0.75 | MEN1 (0.67) | MAPTMEN1HTTKMT2ARAB9A | |
| Salfluverine SCHEMBL2700016 | 0.74 | P2RX1 (1.00) | P2RX1MAPTSLC2A1P2RX4P2RX7 | |
| SCHEMBL23060405 | 0.74 | MAPT (0.72) | P2RX1MAPTMEN1HTTKMT2A | |
| Hydrochloric Acid SCHEMBL29693050 | 0.74 | KCNK3 (0.86) | P2RX1MAPTMEN1HTTKMT2A | |
| SCHEMBL3473744 | 0.74 | BCL2L1 (0.60) | P2RX1MAPTMEN1HTTKMT2A | |
| SCHEMBL4261337 | 0.74 | P2RX1 (0.66) | P2RX1MAPTMEN1HTTKMT2A | |
| SCHEMBL7182329 | 0.73 | MAPT (0.63) | P2RX1MAPTMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937237-A1 | NOVEL PHLOROGLUCINOL DERIVATIVES HAVING SELECTIN LIGAND ACTIVITY | Revotar Biopharmaceuticals AG (DE) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007039112-A1 | NOVEL PHLOROGLUCINOL DERIVATIVES HAVING SELECTIN LIGAND ACTIVITY | REVOTAR BIOPHARMACEUTICALS AG (DE) | 2007-04-12 | — | — | WO | disclosed |