Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 14/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | PNLIP | P16233 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4592287 | 1.00 | UTS2R (0.38) | UTS2RNPY5RPDK1CASRPNLIP | |
| SCHEMBL4592695 | 0.96 | UTS2R (0.35) | UTS2R | |
| SCHEMBL4592115 | 0.96 | PDK1 (0.36) | NPY5RPDK1 | |
| SCHEMBL4592696 | 0.96 | UTS2R (0.35) | UTS2R | |
| SCHEMBL5047706 | 0.96 | PDK1 (0.36) | NPY5RPDK1 | |
| SCHEMBL4592817 | 0.91 | UTS2R (0.38) | UTS2R | |
| SCHEMBL4592820 | 0.91 | UTS2R (0.38) | UTS2R | |
| SCHEMBL4592462 | 0.89 | UTS2R (0.37) | UTS2R | |
| SCHEMBL4592463 | 0.89 | UTS2R (0.37) | UTS2R | |
| SCHEMBL4592260 | 0.87 | UTS2R (0.36) | UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885691-A1 | C5A RECEPTOR ANTAGONISTS | Jerini AG (DE) | 2008-02-13 | — | — | EP | claimed |
| WO-2006128670-A1 | C5A RECEPTOR ANTAGONISTS | JERINI AG (DE) | 2006-12-07 | — | — | WO | claimed |