Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.50 |
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2032469 | 0.87 | ADRB2 (0.54) | ADRB2OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL382596 | 0.87 | ADRB2 (0.54) | ADRB2OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL13666761 | 0.87 | ADRB2 (0.54) | ADRB2OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL30504213 | 0.87 | ADRB2 (0.54) | ADRB2OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL148751 | 0.87 | ADRB2 (0.54) | ADRB2OPRM1OPRD1OPRK1OPRL1 | |
| Hydrochloric Acid SCHEMBL19205719 | 0.85 | ADRB2 (0.52) | ADRB2OPRM1OPRD1OPRK1OPRL1 | |
| Hydrochloric Acid SCHEMBL2149707 | 0.85 | ADRB2 (0.52) | ADRB2OPRM1OPRD1OPRK1OPRL1 | |
| Hydrochloric Acid SCHEMBL1002485 | 0.85 | ADRB2 (0.52) | ADRB2OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL56723 | 0.79 | ADRB2 (0.56) | ADRB2AOC3HTT | |
| SCHEMBL157927 | 0.79 | ADRB2 (0.56) | ADRB2AOC3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919861-A2 | COMPOUNDS FOR TREATING ALZHEIMER'S DISEASE | Boehringer Ingelheim International GmbH (DE) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007017511-A2 | COMPOUNDS FOR TREATING ALZHEIMER'S DISEASE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-02-15 | — | — | WO | disclosed |