SCHEMBL459276

SCHEMBL459276

CC(C)=CCNc1ncnc2nc[nH]c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 4/20 1.00
▸ CDK2 P24941 2/20 1.00
▸ TSHR P16473 5/20 0.78
▸ RECQL P46063 2/20 0.78
▸ HTT P42858 4/20 0.60
▸ CYP3A4 P08684 2/20 0.60
▸ HIF1A Q16665 1/20 0.58
▸ HSD17B10 Q99714 3/20 0.56
▸ TP53 P04637 2/20 0.56
▸ LMNA P02545 4/20 0.56
▸ PRMT1 Q99873 1/20 0.53
▸ MAPK1 P28482 2/20 0.52
▸ CYP2D6 P10635 1/20 0.52
▸ BRAF P15056 1/20 0.51
▸ TAAR1 Q96RJ0 1/20 0.50
▸ SMN1; SMN2 Q16637 3/20 0.48
▸ HDAC1 Q13547 1/20 0.48
▸ HDAC2 Q92769 1/20 0.48
▸ MEN1 O00255 1/20 0.48
▸ KMT2A Q03164 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29371127 1.00 CYP1A2 (1.00) CYP1A2CDK2TSHRRECQLHTT
SCHEMBL30320042 0.93 CYP1A2 (0.87) CYP1A2CDK2TSHRRECQLHTT
SCHEMBL10345015 0.89 CYP1A2 (0.80) CYP1A2CDK2TSHRRECQLHTT
SCHEMBL25176316 0.87 TSHR (1.00) CYP1A2CDK2TSHRRECQLHTT
SCHEMBL29412055 0.87 TSHR (1.00) CYP1A2CDK2TSHRRECQLHTT
SCHEMBL29350488 0.87 TSHR (1.00) CYP1A2CDK2TSHRRECQLHTT
SCHEMBL1944933 0.87 TSHR (1.00) CYP1A2CDK2TSHRRECQLHTT
SCHEMBL49690 0.87 TSHR (1.00) CYP1A2CDK2TSHRRECQLHTT
SCHEMBL10344950 0.86 CYP1A2 (0.76) CYP1A2CDK2TSHRRECQLHTT
Hydrochloric Acid SCHEMBL27865862 0.86 TSHR (0.97) CYP1A2CDK2TSHRRECQLHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 432 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250376691-A1 FLOTATION OF CULTURED EMBRYO EXPLANTS FOR IMPROVED PLANT REGENERATION EFFICIENCY MONSANTO TECHNOLOGY LLC (US) 2025-12-11 — — US claimed
US-20250268165-A1 METHOD FOR PRODUCING HAPLOID AND DOUBLED HAPLOID SUNFLOWER PLANTS BY MICROSPORE CULTURE KWS SAAT SE & Co. KGaA (DE) 2025-08-28 — — US claimed
WO-2025133120-A1 METHOD FOR PRODUCING HAPLOID AND DOUBLED HAPLOID SUNFLOWER PLANTS IN A DOUBLE LAYER SYSTEM MICROSPORE CULTURE KWS SAAT SE & Co. KGaA (DE) 2025-06-26 — — WO claimed
CN-120082500-A Method for preparing single plant cell 北京艾普希隆生物科技有限公司 2025-06-03 — — CN claimed
EP-4547012-A1 METHOD FOR PRODUCING HAPLOID AND DOUBLED HAPLOID SUNFLOWER PLANTS BY MICROSPORE CULTURE KWS SAAT SE & Co. KGaA (DE) 2025-05-07 — — EP claimed
CN-119546182-A Method for producing haploid/doubled haploid sunflower plants by microspore culture 科沃施种子欧洲股份两合公司 2025-02-28 — — CN claimed
EP-4504948-A1 COMPOSITIONS AND METHODS FOR TRANSFORMATION OF EMBRYO EXPLANT POPULATIONS Monsanto Technology LLC (US) 2025-02-12 — — EP claimed
CN-119212552-A Dedifferentiated plant cells of paeonia, extract thereof and cosmetic use thereof 莱雅公司 2024-12-27 — — CN claimed
EP-4472642-A1 HETEROCYCLIC PURINE CYTOKININ DERIVATIVES, THEIR USE IN WOUND HEALING AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE DERIVATIVES Univerzita Palackého v Olomouci (CZ) 2024-12-11 — — EP claimed
US-20240301435-A1 COMPOSITIONS AND METHODS FOR TRANSFORMATION OF MONOCOT SEED EXCISED EMBRYO EXPLANTS MONSANTO TECHNOLOGY LLC 2024-09-12 — — US claimed
US-20040251197-A1 Adding at least one cell signalling chemical (CSC) such as a bacterial pheromone, a eulcaryotic hormone or a diffusible communication molecule to a sewage substrate, wherein the CSC regulates activity in at least one microbial population in the sewage substrate ADVANCED ENVIRONMENTAL TECHNOLOGIES PTY LTD. (AU) 2004-12-16 — — US claimed
EP-1436234-A1 ORGANIC WASTE TREATMENT Advanced Environmental Technologies Pty. Ltd. (AU) 2004-07-14 — — EP claimed
EP-1164831-B1 MICROPROPAGATION AND PRODUCTION OF PHYTOPHARMACEUTICAL PLANTS UNIV GUELPH (CA) 2003-11-05 — — EP claimed
WO-2003033418-A1 ORGANIC WASTE TREATMENT ADVANCED ENVIRONMENTAL TECHNOLOGIES PTY. LTD. (AU) 2003-04-24 — — WO claimed
EP-1164831-A2 MICROPROPAGATION AND PRODUCTION OF PHYTOPHARMACEUTICAL PLANTS University of Guelph (CA) 2002-01-02 — — EP claimed
WO-2000057690-A2 MICROPROPAGATION AND PRODUCTION OF PHYTOPHARMACEUTICAL PLANTS UNIVERSITY OF GUELPH (CA) 2000-10-05 — — WO claimed
US-5573941-A TREATING CALLUS WITH FERULIC ACID TO INCREASE VANILLIN PRODUCTION, STIMULATING CALLUS GROWTH WITH HORMONE UNIVERSITY OF DELAWARE (US) 1996-11-12 — — US claimed
EP-0450344-B1 Method for the production of pilocarpin from vitro-cultures of Pilocarpus MERCK PATENT GMBH (DE) 1996-01-10 — — EP claimed
EP-0450344-A2 Method for the production of pilocarpin from vitro-cultures of Pilocarpus MERCK PATENT GmbH (DE) 1991-10-09 — — EP claimed
US-4377921-A Method for the in situ activation of the needle fascicles of gymnosperms and for the clonal propagation of gymnosperms and the clones produced thereby INTERNATIONAL PAPER COMPANY (US) 1983-03-29 — — US claimed
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