SCHEMBL1944933

SCHEMBL1944933

C/C(=C\CNc1ncnc2nc[nH]c12)CO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 5/20 1.00
▸ RECQL P46063 2/20 1.00
▸ CYP1A2 P05177 4/20 0.78
▸ CDK2 P24941 2/20 0.78
▸ CYP3A4 P08684 2/20 0.59
▸ HTT P42858 4/20 0.56
▸ HIF1A Q16665 1/20 0.55
▸ HSD17B10 Q99714 3/20 0.53
▸ TP53 P04637 2/20 0.53
▸ LMNA P02545 4/20 0.52
▸ PRMT1 Q99873 1/20 0.50
▸ MAPK1 P28482 2/20 0.49
▸ CYP2D6 P10635 1/20 0.49
▸ BRAF P15056 1/20 0.48
▸ TAAR1 Q96RJ0 1/20 0.47
▸ SMN1; SMN2 Q16637 3/20 0.45
▸ HDAC1 Q13547 1/20 0.45
▸ HDAC2 Q92769 1/20 0.45
▸ MEN1 O00255 1/20 0.45
▸ KMT2A Q03164 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL49690 1.00 TSHR (1.00) TSHRRECQLCYP1A2CDK2CYP3A4
SCHEMBL25176316 1.00 TSHR (1.00) TSHRRECQLCYP1A2CDK2CYP3A4
SCHEMBL29412055 1.00 TSHR (1.00) TSHRRECQLCYP1A2CDK2CYP3A4
SCHEMBL29350488 1.00 TSHR (1.00) TSHRRECQLCYP1A2CDK2CYP3A4
Hydrochloric Acid SCHEMBL584649 0.99 TSHR (0.97) TSHRRECQLCYP1A2CDK2CYP3A4
Hydrochloric Acid SCHEMBL27865862 0.99 TSHR (0.97) TSHRRECQLCYP1A2CDK2CYP3A4
Alcohol SCHEMBL28719125 0.97 TSHR (0.95) TSHRRECQLCYP1A2CDK2CYP3A4
SCHEMBL30320048 0.94 TSHR (0.88) TSHRRECQLCYP1A2CDK2CYP3A4
Phosphoric Acid SCHEMBL3301229 0.94 TSHR (0.88) TSHRRECQLCYP1A2CDK2CYP3A4
Phosphoric Acid SCHEMBL29264659 0.94 TSHR (0.88) TSHRRECQLCYP1A2CDK2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4472642-A1 HETEROCYCLIC PURINE CYTOKININ DERIVATIVES, THEIR USE IN WOUND HEALING AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE DERIVATIVES Univerzita Palackého v Olomouci (CZ) 2024-12-11 — — EP claimed
EP-4153592-B1 MESYLATE SALTS OF HETEROCYCLIC CYTOKININS, COMPOSITIONS CONTAINING THESE DERIVATIVES AND USE THEREOF UNIV PALACKEHO (CZ) 2024-04-24 — — EP claimed
WO-2023078482-A1 HETEROCYCLIC PURINE CYTOKININ DERIVATIVES, THEIR USE IN WOUND HEALING AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE DERIVATIVES Univerzita Palackého v Olomouci (CZ) 2023-05-11 — — WO claimed
EP-0827532-B1 REGENERATION OF BOTH PLANT TISSUES AND TRANSGENIC PLANT TISSUES USING A NEW PLANT HORMONE, 5-BROMOINDOLE-3-ACETIC ACID INVITROGEN CORP (US) 2003-12-10 — — EP claimed
US-5188655-A Plant growth regulators; synergistic FLORATINE PRODUCTS GROUP, INC. 1993-02-23 — — US claimed
EP-4691240-A1 SUPPLEMENT AND NUTRITIVE SUBSTRATE COMPOSITIONS, SYNTHETIC SEED, METHOD FOR CULTIVATING PLANTS, AND, USE OF A SUPPLEMENT COMPOSITION CTC - Centro de Tecnologia Canavieira S.A. (BR) 2026-02-11 — — EP disclosed
US-20250381110-A1 SKIN CARE COMPOSITION AND METHOD OF USING THE SAME PROCTER & GAMBLE (US) 2025-12-18 — — US disclosed
EP-4577181-A1 ORAL CARE COMPOSITIONS Adyani Consulting Corp. (US) 2025-07-02 — — EP disclosed
CN-119818548-A Skin improving composition comprising culture of Parsley 生物 FD&C 株式会社 2025-04-15 — — CN disclosed
EP-4472642-A1 HETEROCYCLIC PURINE CYTOKININ DERIVATIVES, THEIR USE IN WOUND HEALING AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE DERIVATIVES Univerzita Palackého v Olomouci (CZ) 2024-12-11 — — EP disclosed
EP-4384627-A1 HETEROLOGOUS PRODUCTION OF CYTOKININS IN YEASTS Adama Chile SA (CL) 2024-06-19 — — EP disclosed
CN-118202058-A Heterologous production of cytokinins in yeast 安道麦智利股份有限公司 2024-06-14 — — CN disclosed
WO-2004092345-A2 TRANSFORMATION OF BRASSICA CARGILL INCORPORATED (US) 2004-10-28 — — WO disclosed
WO-2004090143-A2 MODULATION OF CYTOKININ ACTIVITY IN PLANTS PIONEER HI-BRED INTERNATIONAL, INC. (US) 2004-10-21 — — WO disclosed
US-6617497-B1 Transformed plant comprising a nucleic acid encoding a protein that exhibits enzymatic activity; can use to alter pathogen resistance and plant growth properties THE CURATORS OF THE UNIVERSITY OF MISSOURI 2003-09-09 — — US disclosed
EP-1171619-A1 REGULATED EXPRESSION OF GENES IN PLANT SEEDS PIONEER HI-BRED INTERNATIONAL, INC. (US) 2002-01-16 — — EP disclosed
US-6229066-B1 AMINO ACID AND NUCLEOTIDE SEQUENCE; TRANSGENIC PLANTS WITH ALTERED PROPERTIES SUCH AS DISEASE RESISTANCE, INCREASED GRAIN PRODUCTION, OR MORE DESIRABLE SECONDARY GROWTH CHARACTERISTICS; RECOMBINANT CULTURE PRODUCTION THE CURATORS OF THE UNIVERSITY OF MISSOURI 2001-05-08 — — US disclosed
WO-2000063401-A1 REGULATED EXPRESSION OF GENES IN PLANT SEEDS PIONEER HI-BRED INTERNATIONAL, INC. (US) 2000-10-26 — — WO disclosed
EP-1002096-A1 CYTOKININ OXIDASE THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2000-05-24 — — EP disclosed
WO-1999006571-A1 CYTOKININ OXIDASE THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 1999-02-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250381110-A1 SKIN CARE COMPOSITION AND METHOD OF USING THE SAME SQSTM1, BECN1, CUTA TSHR 4819/4885RECQL 482/4885CYP1A2 4552/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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