Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 8/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4592967 | 0.91 | F10 (0.42) | F10F2USP30POLBHTT | |
| SCHEMBL3878969 | 0.91 | F10 (0.49) | F10F2USP30POLBHTT | |
| SCHEMBL220506 | 0.84 | F10 (0.55) | F10F2USP30POLBDEGS1 | |
| SCHEMBL3878974 | 0.81 | F10 (0.49) | F10F2USP30POLBHTT | |
| SCHEMBL3877246 | 0.79 | F10 (0.43) | F10F2USP30POLBDEGS1 | |
| SCHEMBL3872358 | 0.69 | MAPK1 (0.32) | NPSR1 | |
| SCHEMBL3875568 | 0.68 | F10 (0.53) | F10F2 | |
| SCHEMBL219872 | 0.66 | F10 (0.63) | F10SMN1; SMN2 | |
| SCHEMBL219860 | 0.65 | F10 (0.65) | F10SMN1; SMN2 | |
| SCHEMBL3877037 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888567-A1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | Sanofi-Aventis (FR) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006122661-A1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | SANOFI-AVENTIS (DE) | 2006-11-23 | — | — | WO | disclosed |