Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4592966 | 0.91 | F10 (0.42) | F10F2POLBUSP30HTT | |
| SCHEMBL3878974 | 0.91 | F10 (0.49) | F10F2POLBUSP30RAB9A | |
| SCHEMBL220506 | 0.87 | F10 (0.55) | F10F2POLBUSP30RAB9A | |
| SCHEMBL3877246 | 0.82 | F10 (0.43) | F10F2POLBUSP30DEGS1 | |
| SCHEMBL3878969 | 0.81 | F10 (0.49) | F10F2POLBUSP30HTT | |
| SCHEMBL219872 | 0.69 | F10 (0.63) | F10 | |
| SCHEMBL220656 | 0.68 | F10 (0.59) | F10F2HTT | |
| SCHEMBL219860 | 0.67 | F10 (0.65) | F10 | |
| SCHEMBL3872360 | 0.67 | MAPK1 (0.31) | — | |
| SCHEMBL222025 | 0.67 | F10 (0.59) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888567-A1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | Sanofi-Aventis (FR) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006122661-A1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | SANOFI-AVENTIS (DE) | 2006-11-23 | — | — | WO | disclosed |