Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL180684 | 0.88 | DGAT1 (0.67) | DGAT1SOAT1 | |
| SCHEMBL180790 | 0.85 | DGAT1 (0.66) | DGAT1SOAT1 | |
| SCHEMBL181103 | 0.84 | DGAT1 (0.76) | DGAT1SOAT1 | |
| SCHEMBL180745 | 0.84 | DGAT1 (0.69) | DGAT1SOAT1 | |
| SCHEMBL180905 | 0.83 | DGAT1 (0.68) | DGAT1SOAT1 | |
| SCHEMBL180500 | 0.83 | DGAT1 (0.66) | DGAT1SOAT1 | |
| SCHEMBL181083 | 0.83 | DGAT1 (0.66) | DGAT1SOAT1 | |
| SCHEMBL180517 | 0.83 | DGAT1 (0.66) | DGAT1SOAT1 | |
| Pradigastat SCHEMBL180536 | 0.82 | DGAT1 (1.00) | DGAT1SOAT1 | |
| Pradigastat SCHEMBL1289309 | 0.82 | DGAT1 (1.00) | DGAT1SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004607-A2 | NEW COMPOUNDS | Novartis AG (CH) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007126957-A2 | NEW COMPOUNDS | NOVARTIS AG (CH) | 2007-11-08 | — | — | WO | disclosed |