Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26616615 | 0.98 | TSHR (0.58) | TSHRFAAHTRPV1MEN1THRB | |
| SCHEMBL29956930 | 0.98 | TSHR (0.58) | TSHRFAAHTRPV1MEN1THRB | |
| SCHEMBL1236602 | 0.98 | TSHR (0.58) | TSHRFAAHTRPV1MEN1THRB | |
| SCHEMBL9747592 | 0.98 | TSHR (0.58) | TSHRFAAHTRPV1MEN1THRB | |
| SCHEMBL14201441 | 0.98 | TSHR (0.58) | TSHRFAAHTRPV1MEN1THRB | |
| SCHEMBL1236838 | 0.98 | TSHR (0.58) | TSHRFAAHTRPV1MEN1THRB | |
| SCHEMBL10586641 | 0.98 | TSHR (0.58) | TSHRFAAHTRPV1MEN1THRB | |
| SCHEMBL3946404 | 0.98 | TSHR (0.58) | TSHRFAAHTRPV1MEN1THRB | |
| SCHEMBL21153537 | 0.98 | TSHR (0.58) | TSHRFAAHTRPV1MEN1THRB | |
| SCHEMBL28043548 | 0.98 | TSHR (0.58) | TSHRFAAHTRPV1MEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| EP-1876196-A1 | VOC free or low VOC polyurethane coating | Sika Technology AG (CH) | 2008-01-09 | — | — | EP | disclosed |