Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | FAAH | O00519 | 2/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | ADH1B | P00325 | 1/20 | 0.43 |
| ▸ | ADH1C | P00326 | 1/20 | 0.43 |
| ▸ | ADH1A | P07327 | 1/20 | 0.43 |
| ▸ | ADH4 | P08319 | 1/20 | 0.43 |
| ▸ | ADH7 | P40394 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28043548 | 1.00 | TSHR (0.58) | TSHRFAAHTRPV1HTTMEN1 | |
| SCHEMBL14201441 | 1.00 | TSHR (0.58) | TSHRFAAHTRPV1HTTMEN1 | |
| SCHEMBL26616615 | 1.00 | TSHR (0.58) | TSHRFAAHTRPV1HTTMEN1 | |
| SCHEMBL1236838 | 1.00 | TSHR (0.58) | TSHRFAAHTRPV1HTTMEN1 | |
| SCHEMBL9747592 | 1.00 | TSHR (0.58) | TSHRFAAHTRPV1HTTMEN1 | |
| SCHEMBL21153537 | 1.00 | TSHR (0.58) | TSHRFAAHTRPV1HTTMEN1 | |
| SCHEMBL29956930 | 1.00 | TSHR (0.58) | TSHRFAAHTRPV1HTTMEN1 | |
| SCHEMBL3946404 | 1.00 | TSHR (0.58) | TSHRFAAHTRPV1HTTMEN1 | |
| SCHEMBL10586641 | 1.00 | TSHR (0.58) | TSHRFAAHTRPV1HTTMEN1 | |
| SCHEMBL2030564 | 0.98 | TSHR (0.56) | TSHRFAAHTRPV1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6726915-B2 | DIAMIDE COMPOUNDS RETAINING GOOD COSMETIC PROPERTIES, IN PARTICULAR A CERTAIN LEVEL OF | L'OREAL (FR) | 2004-04-27 | — | — | US | claimed |
| US-20030129211-A9 | Cosmetic or pharmaceutical composition in solid form comprising bis-acyl-amides | L'OREAL S.A. (FR) | 2003-07-10 | — | — | US | claimed |
| US-20020150602-A1 | Cosmetic or pharmaceutical composition in solid form comprising bis-acyl-amides | LIVOREIL AUDE (FR) | 2002-10-17 | — | — | US | claimed |
| EP-1676556-B1 | Cosmetic composition containing a polyorganosiloxane polymer | OREAL (FR) | 2012-01-11 | — | — | EP | disclosed |
| US-20110189117-A1 | COSMETIC COMPOSITION CONTAINING A POLYORGANISILOXANE POLYMER | L'OREAL (FR) | 2011-08-04 | — | — | US | disclosed |
| US-7879316-B2 | Mixture of polyamide-siloxane copolymer in volatile oil; cosmetics | L'OREAL (FR) | 2011-02-01 | — | — | US | disclosed |
| US-7820146-B2 | Care and/or make-up cosmetic composition structured with silicone polymers and organogelling agents, in rigid form | L'OREAL S.A. (FR) | 2010-10-26 | — | — | US | disclosed |
| US-7803356-B2 | Compositions containing at least one silicone resin and a volatile non-cyclic silicone oil | L'OREAL (FR) | 2010-09-28 | — | — | US | disclosed |
| US-7758848-B2 | Cosmetic composition containing a polyorganosiloxane polymer | L'OREAL (FR) | 2010-07-20 | — | — | US | disclosed |
| US-20080057011-A1 | Composition structured with a polymer containing a heteroatom and an Organogelator | L'OREAL S.A., | 2008-03-06 | — | — | US | disclosed |
| EP-1676556-A2 | Cosmetic composition containing a polyorganosiloxane polymer | L'OREAL (FR) | 2006-07-05 | — | — | EP | disclosed |
| US-20040223987-A1 | Composition structured with a polymer containing a heteroatom and organogelator | L'OREAL S.A. (FR) | 2004-11-11 | — | — | US | disclosed |
| US-20040170586-A1 | Cosmetic composition containing a polyorganosiloxane polymer | L'OREAL (FR) | 2004-09-02 | — | — | US | disclosed |
| US-6726915-B2 | DIAMIDE COMPOUNDS RETAINING GOOD COSMETIC PROPERTIES, IN PARTICULAR A CERTAIN LEVEL OF | L'OREAL (FR) | 2004-04-27 | — | — | US | disclosed |
| WO-2003105788-A2 | CARE AND/OR MAKE-UP COSMETIC COMPOSITION STRUCTURED WITH SILICONE POLYMERS AND ORGANOGELLING AGENTS, IN RIGID FORM | L'OREAL (FR) | 2003-12-24 | — | — | WO | disclosed |
| US-20030129211-A9 | Cosmetic or pharmaceutical composition in solid form comprising bis-acyl-amides | L'OREAL S.A. (FR) | 2003-07-10 | — | — | US | disclosed |
| EP-1294342-A2 | COMPOSITION STRUCTURED WITH A POLYMER CONTAINING AHETEROATOM AND AN ORGANOGELATOR | L'OREAL (FR) | 2003-03-26 | — | — | EP | disclosed |
| US-20020150602-A1 | Cosmetic or pharmaceutical composition in solid form comprising bis-acyl-amides | LIVOREIL AUDE (FR) | 2002-10-17 | — | — | US | disclosed |
| WO-2002055030-A2 | COMPOSITION STRUCTURED WITH A POLYMER CONTAINING A HETEROATOM AND ORGANOGELATOR | OREAL (FR) | 2002-07-18 | — | — | WO | disclosed |
| WO-2002047628-A1 | COMPOSITION STRUCTURED WITH A POLYMER CONTAINING A HETEROATOM AND AN ORGANOGELATOR | L'ORÉAL (FR) | 2002-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080057011-A1 | Composition structured with a polymer containing a heteroatom and an Organogelator | CUTA, FABP4, PARG | TSHR 3188/4885FAAH 80/4885TRPV1 1427/4885 |
| US-20040223987-A1 | Composition structured with a polymer containing a heteroatom and organogelator | CUTA, PARG, FABP4 | TSHR 3769/4885FAAH 72/4885TRPV1 1283/4885 |
| US-20030129211-A9 | Cosmetic or pharmaceutical composition in solid form comprising bis-acyl-amides | FAAH, HRH1, HRH4 | TSHR 991/4885FAAH 1/4885TRPV1 412/4885 |
| US-20040170586-A1 | Cosmetic composition containing a polyorganosiloxane polymer | CUTA, XPA, PRDX1 | TSHR 4303/4885FAAH 2104/4885TRPV1 652/4885 |
| US-20020150602-A1 | Cosmetic or pharmaceutical composition in solid form comprising bis-acyl-amides | FAAH, HRH1, HRH4 | TSHR 991/4885FAAH 1/4885TRPV1 412/4885 |
| US-20110189117-A1 | COSMETIC COMPOSITION CONTAINING A POLYORGANISILOXANE POLYMER | CUTA, PRDX1, PRXL2A | TSHR 3985/4885FAAH 2611/4885TRPV1 620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.