Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 3/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL220137 | 1.00 | HTT (0.47) | HTTSYKLMNASMN1; SMN2CA12 | |
| SCHEMBL24635967 | 0.83 | SYK (0.65) | HTTSYKLMNASMN1; SMN2CA12 | |
| SCHEMBL4362880 | 0.81 | SYK (0.49) | HTTSYKLMNASMN1; SMN2CA12 | |
| SCHEMBL22775253 | 0.81 | SYK (0.55) | HTTSYKLMNASMN1; SMN2CA12 | |
| SCHEMBL13618133 | 0.80 | SYK (0.48) | HTTSYKLMNASMN1; SMN2CA12 | |
| SCHEMBL10402060 | 0.79 | SYK (0.47) | HTTSYKLMNASMN1; SMN2CA12 | |
| SCHEMBL10402059 | 0.79 | SYK (0.47) | HTTSYKLMNASMN1; SMN2CA12 | |
| SCHEMBL221316 | 0.79 | CA12 (0.51) | HTTSYKLMNASMN1; SMN2CA12 | |
| SCHEMBL6315326 | 0.78 | MAOB (0.45) | SYKCTSSCTSLL3MBTL1 | |
| SCHEMBL7243564 | 0.78 | MAOB (0.45) | SYKCTSSCTSLL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888567-A1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | Sanofi-Aventis (FR) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006122661-A1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | SANOFI-AVENTIS (DE) | 2006-11-23 | — | — | WO | disclosed |