Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12205354 | 0.88 | SYK (0.56) | SYKMAPTPSMB5CTSSPPARA | |
| SCHEMBL220137 | 0.83 | HTT (0.47) | SYKCA12CA1HTTLMNA | |
| SCHEMBL4593136 | 0.83 | HTT (0.47) | SYKCA12CA1HTTLMNA | |
| SCHEMBL7026898 | 0.83 | SYK (0.70) | SYKMAPTHTTLMNASMN1; SMN2 | |
| SCHEMBL7910002 | 0.83 | SYK (0.70) | SYKMAPTHTTLMNASMN1; SMN2 | |
| SCHEMBL30500935 | 0.83 | SYK (0.70) | SYKMAPTHTTLMNASMN1; SMN2 | |
| SCHEMBL569003 | 0.82 | SERPINE1 (0.43) | SYKCA12CA1CA7CA14 | |
| SCHEMBL7022981 | 0.82 | SYK (0.68) | SYKMAPTHTTLMNASMN1; SMN2 | |
| SCHEMBL30500895 | 0.81 | SYK (0.60) | SYKMAPTHTTLMNASMN1; SMN2 | |
| SCHEMBL15109532 | 0.80 | SYK (0.58) | SYKMAPTCA12CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4074709-A1 | MONOCYCLIC BETA-LACTAM COMPOUND AND USE THEREOF | Evopoint Biosciences Co., Ltd. (CN) | 2022-10-19 | — | — | EP | disclosed |