Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.41 |
| ▸ | LSS | P48449 | 2/20 | 0.40 |
| ▸ | CHKA | P35790 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL223203 | 0.81 | CHKA (0.59) | LSSCHKADPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL784685 | 0.79 | CHKA (0.57) | LSSCHKADPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL1060872 | 0.79 | CHKA (0.57) | LSSCHKADPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL7328290 | 0.77 | CHKA (0.55) | LSSCHKADPP4DPP8DPP9 | |
| SCHEMBL219902 | 0.76 | KDM1A (0.42) | F10LSSCHKADPP4DPP8 | |
| Trifluoroacetic Acid SCHEMBL1456945 | 0.73 | DPP4 (0.59) | LSSCHKADPP4DPP8DPP9 | |
| SCHEMBL14275562 | 0.71 | CHKA (0.50) | CHKADPP4DPP8DPP9DPP7 | |
| Isophthalic Acid SCHEMBL27902625 | 0.70 | KMO (0.49) | F10LSSDPP4DPP8DPP9 | |
| SCHEMBL785766 | 0.70 | CHKA (0.50) | F10LSSCHKADPP4DPP8 | |
| SCHEMBL785122 | 0.70 | CHKA (0.53) | F10CHKADPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888567-A1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | Sanofi-Aventis (FR) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006122661-A1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | SANOFI-AVENTIS (DE) | 2006-11-23 | — | — | WO | disclosed |